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Levobupivacaine hydrochloride is a long-acting amide local anaesthetic. Levobupivacaine hydrochloride exerts anaesthetic and analgesic effects through reversible blockade of neuronal sodium channel. Levobupivacaine hydrochloride is metabolized by hepatic cytochrome P450 (CYP450) enzymes in vivo. Levobupivacaine hydrochloride can also induce ferroptosis by miR-489-3p/SLC7A11 signaling in gastric cancer.
| Molecular Weight | 324.89 |
| Formula | C18H28N2O.HCl |
| CAS Number | 27262-48-2 |
| Solubility (25°C) | DMSO 90 mg/mL Water 50 mg/mL |
| Storage | 4°C, dry, sealed |
[2] Chantal A A Heppolette, et al. Clinical Pharmacokinetics and Pharmacodynamics of Levobupivacaine
[5] P H Rosenberg, et al. Levobupivacaine base and levobupivacaine hydrochloride
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