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Bupivacaine hydrochloride is a NMDA receptor inhibitor.Bupivacaine can block sodium, L-calcium, and potassium channels.Bupivacaine potently blocks SCN5A channels with the IC50 of 69.5 μM. Bupivacaine hydrochloride can be used for the research of chronic pain. Bupivacaine hydrochloride reversibly inhibits the SK2 channel in a dose-dependent manner with the IC 50 of 16.5 µM.
| Molecular Weight | 324.89 |
| Formula | C18H28N2O.HCl |
| CAS Number | 18010-40-7 |
| Solubility (25°C) | DMSO 25 mg/mL Water 12 mg/mL |
| Storage | 2-8°C, dry, sealed, protect from light |
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