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Benidipine hydrochloride is a hydrochloride salt form of benidipine which is a dihydropyridine calcium channel blocker. Benidipine hydrochloride is used for the treatment of high blood pressure (hypertension). Benidipine hydrochloride reveals a wide range of activities in vitro and in vivo. Benidipine hydrochloride inhibits L-, N- and T-type Ca2+ channels. Benidipine hydrochloride also prevents aldosterone- induced mineralocorticoid receptor activation. Benidipine hydrochloride exhibits cardioprotective and antiartherosclerotic effects.
| Molecular Weight | 542.02 |
| Formula | C28H31N3O6.HCl |
| CAS Number | 91599-74-5 |
| Solubility (25°C) | DMSO |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[3] Sinan Akbayram, et al. Benidipine hydrochloride intoxication in a child
[5] Y Fujimura, et al. Efficacy of benidipine hydrochloride on myocardial ischemia and reperfusion
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