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Selamectin is an antiparasitic agent and insect repellent that activates glutamate-gated chloride channels in neurons and pharyngeal muscles to prevent filariasis, lymphatic filariasis and nematode infection. Selamectin is also an effective p-glycoprotein substrate and inhibitor with IC50 of 120 nM.
| Molecular Weight | 769.96 |
| Formula | C43H63NO11 |
| CAS Number | 220119-17-5 |
| Form | Solid |
| Solubility (25°C) | DMSO |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[2] Mingyang Tang, et al. Ivermectin, a potential anticancer drug derived from an antiparasitic drug
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