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Praziquantel

Cat. No. M2162

All AbMole products are for research use only, cannot be used for human consumption.

Praziquantel Structure
Size Price Availability Quantity
500mg USD 30  USD30 In stock
1g USD 40  USD40 In stock
5g USD 50  USD50 In stock
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Quality Control & Documentation
Biological Activity

Praziquantel is a potent, highly effective anthelmintic used in against schistosome and many cestode infestations. Praziquantel inhibits glucose uptake, which lowers glycogen levels and stimulates lactate release. Praziquantel increases the permeability of the membranes of schistosome cells towards calcium ions. Praziquantel causes vacuolization and disintegration of the schistosome tegument.

Chemical Information
Molecular Weight 312.41
Formula C19H24N2O2
CAS Number 55268-74-1
Form Solid
Solubility (25°C) DMSO 50 mg/mL
Ethanol 50 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Tchuenté LA, et al. Am J Trop Med Hyg. Efficacy of praziquantel against Schistosoma haematobium infection in children.

[2] Ridtitid W, et al. Clin Pharmacol Ther. Rifampin markedly decreases plasma concentrations of praziquantel in healthy volunteers.

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