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Amiloride hydrochloride (Midamor), a pyrazine compound inhibit sodium reabsorption through sodium channels in renal epithelial cells. This inhibition creates a negative potential in the luminal membranes of principal cells, located in the distal convoluted tubule and collecting duct. Negative potential reduces secretion of potassium and hydrogen ions. Amiloride is used in conjunction with diuretics to spare potassium loss.
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Amiloride hydrochloride purchased from AbMole
| Molecular Weight | 266.09 |
| Formula | C6H8ClN7O.HCl |
| CAS Number | 2016-88-8 |
| Solubility (25°C) | DMSO 50 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Qianhui Sun, et al. Amiloride: A review
[2] Venkata Yellepeddi, et al. Stability of extemporaneously compounded amiloride nasal spray
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Products are for research use only. Not for human use. We do not sell to patients.
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