All AbMole products are for research use only, cannot be used for human consumption.

Amiloride hydrochloride (Midamor), a pyrazine compound inhibit sodium reabsorption through sodium channels in renal epithelial cells. This inhibition creates a negative potential in the luminal membranes of principal cells, located in the distal convoluted tubule and collecting duct. Negative potential reduces secretion of potassium and hydrogen ions. Amiloride is used in conjunction with diuretics to spare potassium loss.
J Med Virol. 2022 Sep 2.
Enterovirus-71 utilizes small extracellular vesicles to cross the blood-brain barrier for infecting the central nervous system via transcytosis
Amiloride hydrochloride purchased from AbMole
BioRxiv. 2022 May 03;490380.
Multi-omics analyses of drug repurposing reveal Acebutolol and Amiloride for osteoporosis treatment
Amiloride hydrochloride purchased from AbMole
| Molecular Weight | 266.09 |
| Formula | C6H8ClN7O.HCl |
| CAS Number | 2016-88-8 |
| Solubility (25°C) | DMSO 50 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Qianhui Sun, et al. Amiloride: A review
[2] Venkata Yellepeddi, et al. Stability of extemporaneously compounded amiloride nasal spray
| Related Sodium Channel Products |
|---|
| A-803467
A-803467 is a potent and selective Nav1.8 sodium channel blocker that potently blocks tetrodotoxin-resistant currents (IC50 = 140 nM). |
| Ambroxol hydrochloride
AmbroxolHCl is a potent inhibitor of the neuronal Na+ channels, inhibits TTX-resistant Na+ currents with IC50 of 35.2 μM and 22.5 μM for tonic and phasic block, inhibits TTX-sensitive Na+ currents with IC50 of 100 μM. |
| Camostat mesylate
Camostat mesylate is a trypsin-like protease inhibitor, inhibits airway epithelial sodium channel (ENaC) function with IC50 of 50 nM, less potent to trpsin, prostasin and matriptase. |
| Chlorpropamide
Chlorpropamide is a sulfonylurea compound used to study non-insulin-dependent diabetes mellitus (NIDDM). |
| Clopamide
Clopamide is an orally active thiazide-like diuretic agent that inhibits the sodium-coupled chloride cotransporter SLC12A3. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2026 AbMole BioScience. All Rights Reserved.