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Clopamide is an orally active thiazide-like diuretic agent that inhibits the sodium-coupled chloride cotransporter SLC12A3. The venoconstrictor response to bradykinin is attenuated after oral administration of Clopamide (0.5 mg/kg), and by concomitant local infusion of cyclosporine-A (1-10 μg/min) in conscious dogs.
| Molecular Weight | 345.84 |
| Formula | C14H20ClN3O3S |
| CAS Number | 636-54-4 |
| Solubility (25°C) | DMSO ≥ 100 mg/mL |
| Storage | -20°C, sealed |
[1] P H Wise, et al. Clopamide and carbohydrate metabolism
[2] J J McNeil, et al. Clopamide: plasma concentrations and diuretic effect in humans
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