| Cat.No. | Name | Information |
|---|---|---|
| M2206 | TH-302 (Evofosfamide) | TH-302 is a highly potent and selective hypoxia-activated procompound targeting hypoxic regions of solid tumors with IC50 of 19 nM. |
| M6098 | Baicalein | Baicalein is a CYP2C9 and prolyl endopeptidase inhibitor, IC50 value of 3.12 mM. |
| M9325 | EGTA | EGTA is a specific calcium chelator with a Kd of 60.5 nM at physiological pH (7.4) and a high specificity for Ca2+ than for Mg2+.EGTA significantly inhibits the substrate adhesion capacity of inflammatory macrophages. |
| M9330 | Brij-35 | Brij-35 (Polidocanol) is a high HLB, ethoxylated, nonionic ether of lauryl alcohol with broad pH stability. |
| M6154 | 2-PMPA tetrasodium | 2-PMPA (PMPA tetrasodium salt) is a potent and selective inhibitor of glutamate carboxypeptidase II (GCPII) with an IC50 of 300 pM. |
| M2250 | Pamidronate disodium | Pamidronate disodium is a nitrogen containing bisphosphonate, used to the research of preventing osteoporosis. |
| M9916 | DPPH | DPPH (2,2-Diphenyl-1-picrylhydrazyl) is a stable free radical that measures the free radical scavenging activity of antioxidants. |
| M9194 | Insulin (human) | Insulin (human) is a polypeptide hormone that regulates the level of sugar (glucose) in the blood and is produced by beta cells of islets. |
| M3409 | Formestane | Formestane is a second generation selective aromatase inhibitor with an IC50 of 80 nM. |
| M9665 | N-(2-amino-2-oxoethyl)acrylamide | N-(2-Amino-2-oxoethyl)acrylamide |
| M7402 | TES, free acid | TES, free acid is a buffering agent. |
| M7381 | TCS 1105 | TCS 1105 is a gABA A α2 benzodiazepine receptor agonist. |
| M7376 | TC-I 2014 | TC-I 2014 is a potent TRPM8 antagonist. |
| M7343 | SZL P1-41 | SZL P1-41 is a selective Skp2 inhibitor; suppresses E3 ligase activity. |
| M7342 | SYM 2081 | SYM 2081 is a highly selective kainate agonist. |
| M7323 | SR 11302 | SR 11302 is an activator protein-1 (AP-1) transcription factor inhibitor. SR 11302 is a retinoid that specifically inhibits AP-1 activity without activating the transcription of retinoic acid response element (RARE). |
| M7318 | Spermine NONOate | Spermine NONOate is a slow NO releasing agent. |
| M7315 | Nitrosoglutathione | Nitrosoglutathione (GSNO; SNOG) is a exogenous NO donor and a substrate for rat alcohol dehydrogenase class III isoenzyme, inhibits cerebrovascular angiotensin II-dependent and -independent AT1 receptor responses. Breaks down to release NO. |
| M7305 | SKPin C1 | SKPin C1 is a inhibitor of Skp2-mediated p27 degradation. SKPin C1 induces p27 accumulation in metastatic melanoma cell lines. SKPin C1 promotes G1/S cell cycle arrest in T47D cells and LNCaP cells. SKPin C1 induces G2/M cell cycle arrest in MCF-7 cells. |
| M7246 | Sanguinarine chloride | Sanguinarine chloride is a inhibitor of protein phosphatase 2C (PP2C). |
| M7234 | Ryanodine | Ryanodine is a ca2+ release inhibitor. |
| M7152 | Potassium phosphate monobasic | Potassium phosphate monobasic is a commonly used in biological assay buffers. |
| M7119 | PF 06281355 | PF 06281355 is a selective myeloperoxidase (MPO) inhibitor. |
| M7100 | PAF (C16) | PAF (C16) is a platelet-activating factor and ligand for PAF G-protein-coupled receptor (PAFR). C16-PAF exhibits anti-apoptotic effect and inhibits caspase-dependent death by activating the PAFR. C16-PAF is a potent MAPK and MEK/ERK activator. C16-PAF induces increased vascular permeability. |
| M7085 | OR-486 | OR-486 is a catechol O-methyltransferase inhibitor. |
| M7084 | OPC 21268 | OPC 21268 is a orally active vasopressin V1 antagonist. |
| M7073 | O4I2 | O4I2 is a oct3/4 inducer; induces expression of pluripotent-associated genes. |
| M7072 | O4I1 | O4I1 is a oct3/4 inducer. |
| M7066 | NVP 231 | NVP 231 is a potent, selective and reversible CerK inhibitor. |
| M7048 | NS 2028 | NS 2028 is a potent soluble guanylyl cyclase (sGC) inhibitor. |
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