| Cat.No. | Name | Information |
|---|---|---|
| M2206 | TH-302 (Evofosfamide) | TH-302 is a highly potent and selective hypoxia-activated procompound targeting hypoxic regions of solid tumors with IC50 of 19 nM. |
| M6098 | Baicalein | Baicalein is a CYP2C9 and prolyl endopeptidase inhibitor, IC50 value of 3.12 mM. |
| M9325 | EGTA | EGTA is a specific calcium chelator with a Kd of 60.5 nM at physiological pH (7.4) and a high specificity for Ca2+ than for Mg2+.EGTA significantly inhibits the substrate adhesion capacity of inflammatory macrophages. |
| M9330 | Brij-35 | Brij-35 (Polidocanol) is a high HLB, ethoxylated, nonionic ether of lauryl alcohol with broad pH stability. |
| M6154 | 2-PMPA tetrasodium | 2-PMPA (PMPA tetrasodium salt) is a potent and selective inhibitor of glutamate carboxypeptidase II (GCPII) with an IC50 of 300 pM. |
| M2250 | Pamidronate disodium | Pamidronate disodium is a nitrogen containing bisphosphonate, used to the research of preventing osteoporosis. |
| M9916 | DPPH | DPPH (2,2-Diphenyl-1-picrylhydrazyl) is a stable free radical that measures the free radical scavenging activity of antioxidants. |
| M9194 | Insulin (human) | Insulin (human) is a polypeptide hormone that regulates the level of sugar (glucose) in the blood and is produced by beta cells of islets. |
| M3409 | Formestane | Formestane is a second generation selective aromatase inhibitor with an IC50 of 80 nM. |
| M9665 | N-(2-amino-2-oxoethyl)acrylamide | N-(2-Amino-2-oxoethyl)acrylamide |
| M6892 | LAP | LAP (Lithium phenyl-2,4,6-trimethylbenzoylphosphinate) is a water soluble, cytocompatible, Type I photoinitiator for use in the polymerization of hydrogels or other polymeric materials. This photoinitator is preferred over Irgacure 2959 for biological applications due to its increased water solubility, increased polymerization rates with 365 nm light, and absorbance at 400 nm allowing for polymerization with visible light. |
| M6890 | Lalistat 2 | Lalistat 2 is a selective LAL inhibitor. Lalistat 2 is an inhibitor of many lipases especially Lysosomal acid lipase (LAL, IC50 = 152 nM), which is a key enzyme that degrades neutral lipids at an acidic pH in lysosomes. |
| M6866 | KL 001 | KL 001 is a first-in-class cryptochrome protein (CRY) stabilizer that interacts specifically with CRY1 and CRY2 to prevent ubiquitin-dependent CRY degradation, thereby prolonging the circadian cycle. In addition, KL001 has the potential to control fasting hormone-induced gluconeogenesis. |
| M6857 | JX 06 | JX 06 is a potent and selective pyruvate dehydrogenase kinase (PDK) 1/2/3 inhibitor. |
| M6841 | J-147 | J 147 is a neuroprotective and neurotrophic compound; reduces Aβ40 and Aβ42 levels. |
| M6834 | IPTG | IPTG is a used in cloning procedures with X-GAL. |
| M6830 | INH1 | INH1 is a hec1 inhibitor; causes arrest of mitosis. |
| M6814 | IDE 1 | IDE 1 is a induces definitive endoderm formation in mouse and human ESCs. |
| M6756 | GN 44028 | GN 44028 is a potent HIF-1α inhibitor. |
| M6747 | GGsTop | GGsTop is a highly selective and irreversible inhibitor of γ-glutamyl transpeptidase (GGT), with a Ki of 170 μM for Human GGT. |
| M6740 | G-36 | G-36 is a selective GPER antagonist. |
| M6700 | Eeyarestatin I | Eeyarestatin I is a potent endoplasmic reticulum-associated protein degradation (ERAD) and translocation inhibitor. Eeyarestatin I inhibits Sec61 translocon. Eeyarestatin I targets the p97-associated deubiquitinating process (PAD) and inhibits atx3-dependent deubiquitination. |
| M6692 | DSP-4 hydrochloride | DSP-4 hydrochloride is a highly and selective adrenergic neurotoxin. DSP-4 hydrochloride can cross the blood brain barrier. |
| M6672 | DIM-C-pPhOCH3 | DIM-C-pPhOCH3 is an agonist of the orphan receptor nuclear receptor related protein 77 (Nur77). |
| M6648 | Cytosporone B | Cytosporone B is a high affinity nuclear receptor Nur77 agonist (IC50 = 0.278 nM). |
| M6628 | CP 809101 hydrochloride | CP 809101 hydrochloride is a potent and selective 5-HT 2C agonist. |
| M6623 | CORM 2 | CORM 2 is a carbon monoxide-releasing molecule. |
| M6609 | CITCO | CITCO is a selective Constitutive androstane receptor (CAR) agonist. CITCO inhibits growth and expansion of brain tumour stem cells (BTSCs) and has an EC50 of 49 nM over pregnane X receptor (PXR). |
| M6601 | CID 5951923 | CID 5951923 is a krüppel-like factor 5 (KLF5) inhibitor. |
| M6593 | CHES | CHES is a buffering agent. |
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