Cat.No. | Name | Information |
---|---|---|
M2206 | TH-302 (Evofosfamide) | TH-302 is a highly potent and selective hypoxia-activated procompound targeting hypoxic regions of solid tumors with IC50 of 19 nM. |
M6098 | Baicalein | Baicalein is a CYP2C9 and prolyl endopeptidase inhibitor, IC50 value of 3.12 mM. |
M9325 | EGTA | EGTA is a specific calcium chelator with a Kd of 60.5 nM at physiological pH (7.4) and a high specificity for Ca2+ than for Mg2+.EGTA significantly inhibits the substrate adhesion capacity of inflammatory macrophages. |
M9330 | Brij-35 | Brij-35 (Polidocanol) is a high HLB, ethoxylated, nonionic ether of lauryl alcohol with broad pH stability. |
M6154 | 2-PMPA tetrasodium | 2-PMPA (PMPA tetrasodium salt) is a potent and selective inhibitor of glutamate carboxypeptidase II (GCPII) with an IC50 of 300 pM. |
M2250 | Pamidronate disodium | Pamidronate disodium is a nitrogen containing bisphosphonate, used to the research of preventing osteoporosis. |
M9916 | DPPH | DPPH (2,2-Diphenyl-1-picrylhydrazyl) is a stable free radical that measures the free radical scavenging activity of antioxidants. |
M9194 | Insulin (human) | Insulin (human) is a polypeptide hormone that regulates the level of sugar (glucose) in the blood and is produced by beta cells of islets. |
M3409 | Formestane | Formestane is a second generation selective aromatase inhibitor with an IC50 of 80 nM. |
M9665 | N-(2-amino-2-oxoethyl)acrylamide | N-(2-Amino-2-oxoethyl)acrylamide |
M6474 | AY 9944 | AY 9944 is a specific cholesterol biosynthesis inhibitor. AY 9944 inhibits the 7-dehydro cholesterol Δ7-reductase (DHCR7) enzyme with an IC50 of 13 nM. |
M6462 | ARN272 | ARN272 is a fAAH-like anandamide transporter (FLAT) inhibitor. |
M6444 | Andrographolide | Andrographolide is a NF-κB inhibitor that inhibits NF-κB activation by covalently modifying the cysteine residue of P50 in endothelial cells without affecting IκBα degradation or p50/ P65 nuclear translocation. Andrographolide has antiviral effects. |
M6420 | AIM-100 | AIM-100 is a potent and selective Ack1 (TNK2) inhibitor (IC50 = 22 nM). |
M6407 | AdipoRon hydrochloride | AdipoRon hydrochloride is a orally active AdipoR1 and AdipoR2 agonist; antidiabetic. |
M6406 | Adaptaquin | Adaptaquin is a hIF-prolyl hydroxylase-2 (PHD2) inhibitor. Adaptaquin blocks glutamate induced ROS production in HT-22 cells, independent of MnSOD. Adaptaquin exhibits neuroprotective effects and enhances functional recovery in rodent intracerebral hemorrhage models, via inhibition of ATF4 dependent genes. Brain penetrant. Also antioxidant. |
M6395 | Emapunil | Emapunil is a selective TSPO ligand. |
M6353 | 6bK | 6bK is a insulin degrading enzyme (IDE) inhibitor. |
M6311 | GO-203 | GO-203 is a D-amino acid cell-penetrating peptide inhibitor of MUC1-C dimerization and thereby its oncogenic function. |
M6298 | Sodium tartrate | Sodium tartrate has been used in organic synthesis to break up emulsions in aqueous workups. The compound is an ingredient of Fehling's solution and of the reagent Biuret (sc-239384). |
M6265 | BMS 309403 | BMS-309403 is a potent, selective and cell-permeable inhibitor of fatty acid binding protein 4 (FABP4) with a Ki of less than 2 nM. |
M6252 | Sulbutiamine | Sulbutiamine is a highly lipid soluble synthetic analogue of vitamin B1, used for the treatment of asthenia. |
M6228 | Wilforine | Wilforine is a sesquiterpene pyridine alkaloid; important bioactive compound in T. wilfordii plants, and is effective in idiopathic pulmonary fibrosis. |
M6210 | 2-Thenoyltrifluoroacetone | 2-Thenoyltrifluoroacetone, the archetype representative of Complex II inhibitors, binds to the ubiquinone-binding site of Complex II, thereby blocking electron transfer, which causes electron slippage and superoxide production. |
M6208 | 2-Chloro-5-nitro-benzeneacetic acid | |
M6207 | FX1 | FX1 is a potent and specific BCL6 inhibitor, with an IC50 of around 35 μM. |
M6193 | Propacetamol Hydrochloride | Propacetamol is water soluble and can be directly injected. |
M6192 | Cetilistat | Cetilistat is an inhibitor of pancreatic and gastrointestinal lipases. It has great treatment of obesity in both diabetic and non-diabetic patients. |
M6188 | QS11 | QS11 is a GTPase activating protein of ADP-ribosylation factor 1 (ARFGAP1) inhibitor. QS11 modulates Wnt/β-catenin signaling through an effect on protein trafficking. QS11 inhibits migration of ARFGAP overexpressing breast cancer cells. |
M6184 | Dutetrabenazine | Deutetrabenazine is the deuterium labeled Tetrabenazine, which is a VMAT-inhibitor used for the research of hyperkinetic movement disorder. |
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