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Cephalosporin C zinc salt is a potent SAMHD1 inhibitor, with IC50 of 1.1 μM. Cephalosporin C zinc salt is used to study the effect of transpeptidase expression, binding, and inhibition on bacterial cell wall mucopeptide synthesis. Cephalosporin C has been used to determine activity during stopped-flow Fuorescence spectrometric measurements of association.
| Molecular Weight | 478.78 |
| Formula | C16H19N3O8SZn |
| CAS Number | 59143-60-1 |
| Solubility (25°C) | DMSO ≥ 4 mg/mL (adjust pH to 3 with HCl) |
| Storage | 2-8°C, dry, sealed |
[1] Kyle J Seamon, et al. J Biomol Screen. A High-Throughput Enzyme-Coupled Assay for SAMHD1 dNTPase
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