Cat.No. | Name | Information |
---|---|---|
M2206 | TH-302 (Evofosfamide) | TH-302 is a highly potent and selective hypoxia-activated procompound targeting hypoxic regions of solid tumors with IC50 of 19 nM. |
M6098 | Baicalein | Baicalein is a CYP2C9 and prolyl endopeptidase inhibitor, IC50 value of 3.12 mM. |
M9325 | EGTA | EGTA is a specific calcium chelator with a Kd of 60.5 nM at physiological pH (7.4) and a high specificity for Ca2+ than for Mg2+.EGTA significantly inhibits the substrate adhesion capacity of inflammatory macrophages. |
M9330 | Brij-35 | Brij-35 (Polidocanol) is a high HLB, ethoxylated, nonionic ether of lauryl alcohol with broad pH stability. |
M6154 | 2-PMPA tetrasodium | 2-PMPA (PMPA tetrasodium salt) is a potent and selective inhibitor of glutamate carboxypeptidase II (GCPII) with an IC50 of 300 pM. |
M2250 | Pamidronate disodium | Pamidronate disodium is a nitrogen containing bisphosphonate, used to the research of preventing osteoporosis. |
M9916 | DPPH | DPPH (2,2-Diphenyl-1-picrylhydrazyl) is a stable free radical that measures the free radical scavenging activity of antioxidants. |
M9194 | Insulin (human) | Insulin (human) is a polypeptide hormone that regulates the level of sugar (glucose) in the blood and is produced by beta cells of islets. |
M3409 | Formestane | Formestane is a second generation selective aromatase inhibitor with an IC50 of 80 nM. |
M9665 | N-(2-amino-2-oxoethyl)acrylamide | N-(2-Amino-2-oxoethyl)acrylamide |
M6890 | Lalistat 2 | Lalistat 2 is a selective LAL inhibitor. Lalistat 2 is an inhibitor of many lipases especially Lysosomal acid lipase (LAL, IC50 = 152 nM), which is a key enzyme that degrades neutral lipids at an acidic pH in lysosomes. |
M6866 | KL 001 | KL 001 is a first-in-class cryptochrome protein (CRY) stabilizer that interacts specifically with CRY1 and CRY2 to prevent ubiquitin-dependent CRY degradation, thereby prolonging the circadian cycle. In addition, KL001 has the potential to control fasting hormone-induced gluconeogenesis. |
M6857 | JX 06 | JX 06 is a potent and selective pyruvate dehydrogenase kinase (PDK) 1/2/3 inhibitor. |
M6841 | J-147 | J 147 is a neuroprotective and neurotrophic compound; reduces Aβ40 and Aβ42 levels. |
M6834 | IPTG | IPTG is a used in cloning procedures with X-GAL. |
M6830 | INH1 | INH1 is a hec1 inhibitor; causes arrest of mitosis. |
M6814 | IDE 1 | IDE 1 is a induces definitive endoderm formation in mouse and human ESCs. |
M6756 | GN 44028 | GN 44028 is a potent HIF-1α inhibitor. |
M6747 | GGsTop | GGsTop is a highly selective and irreversible inhibitor of γ-glutamyl transpeptidase (GGT), with a Ki of 170 μM for Human GGT. |
M6740 | G-36 | G-36 is a selective GPER antagonist. |
M6700 | Eeyarestatin I | Eeyarestatin I is a potent endoplasmic reticulum-associated protein degradation (ERAD) and translocation inhibitor. Eeyarestatin I inhibits Sec61 translocon. Eeyarestatin I targets the p97-associated deubiquitinating process (PAD) and inhibits atx3-dependent deubiquitination. |
M6692 | DSP-4 hydrochloride | DSP-4 hydrochloride is a highly and selective adrenergic neurotoxin. DSP-4 hydrochloride can cross the blood brain barrier. |
M6672 | DIM-C-pPhOCH3 | DIM-C-pPhOCH3 is an agonist of the orphan receptor nuclear receptor related protein 77 (Nur77). |
M6656 | DCA | DCA (Sodium dichloroacetate) is a mitochondrial pyruvate dehydrogenase kinase (PDK) inhibitor. |
M6648 | Cytosporone B | Cytosporone B is a high affinity nuclear receptor Nur77 agonist (IC50 = 0.278 nM). |
M6628 | CP 809101 hydrochloride | CP 809101 hydrochloride is a potent and selective 5-HT 2C agonist. |
M6623 | CORM 2 | CORM 2 is a carbon monoxide-releasing molecule. |
M6609 | CITCO | CITCO is a selective Constitutive androstane receptor (CAR) agonist. CITCO inhibits growth and expansion of brain tumour stem cells (BTSCs) and has an EC50 of 49 nM over pregnane X receptor (PXR). |
M6601 | CID 5951923 | CID 5951923 is a krüppel-like factor 5 (KLF5) inhibitor. |
M6593 | CHES | CHES is a buffering agent. |
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