Cat.No. | Name | Information |
---|---|---|
M2206 | TH-302 (Evofosfamide) | TH-302 is a highly potent and selective hypoxia-activated procompound targeting hypoxic regions of solid tumors with IC50 of 19 nM. |
M6098 | Baicalein | Baicalein is a CYP2C9 and prolyl endopeptidase inhibitor, IC50 value of 3.12 mM. |
M9325 | EGTA | EGTA is a specific calcium chelator with a Kd of 60.5 nM at physiological pH (7.4) and a high specificity for Ca2+ than for Mg2+.EGTA significantly inhibits the substrate adhesion capacity of inflammatory macrophages. |
M9330 | Brij-35 | Brij-35 (Polidocanol) is a high HLB, ethoxylated, nonionic ether of lauryl alcohol with broad pH stability. |
M6154 | 2-PMPA tetrasodium | 2-PMPA (PMPA tetrasodium salt) is a potent and selective inhibitor of glutamate carboxypeptidase II (GCPII) with an IC50 of 300 pM. |
M2250 | Pamidronate disodium | Pamidronate disodium is a nitrogen containing bisphosphonate, used to the research of preventing osteoporosis. |
M9916 | DPPH | DPPH (2,2-Diphenyl-1-picrylhydrazyl) is a stable free radical that measures the free radical scavenging activity of antioxidants. |
M9194 | Insulin (human) | Insulin (human) is a polypeptide hormone that regulates the level of sugar (glucose) in the blood and is produced by beta cells of islets. |
M3409 | Formestane | Formestane is a second generation selective aromatase inhibitor with an IC50 of 80 nM. |
M9665 | N-(2-amino-2-oxoethyl)acrylamide | N-(2-Amino-2-oxoethyl)acrylamide |
M7989 | PS48 | PS48 is a PDK1 (phosphoinositide-depende |
M7988 | 5Z-7-Oxozeaenol | 5Z-7-oxozeaenol is a potent ATP-competitive irreversible inhibitor of ERK2 (IC50 = 80 nM), TAK1 (MEKK7), MKK7, and MEK1, which all contain a common cysteine residue in the ATP-binding site. |
M7969 | NS3694 | NS3694 is an Inhibitor of apoptosome formation. |
M7966 | Norharmane | Inhibitor of indoleamine 2,3-dioxygenase (IDO). |
M7950 | NO-1886 | Lipoprotein lipase activator. |
M7949 | Nisoxetine hydrochloride | Nisoxetine hydrochloride is a potent, selective norepinephrine transporter inhibitor (Ki = 5.1 nM). |
M7945 | Pimonidazole | Pimonidazole is an effective and nontoxic exogenous 2-nitroimidazole hypoxia marker. Pimonidazole accumulates in hypoxic cells via covalent binding with macromolecules or by forming reductive metabolites after reduction of its nitro group, it can be used for qualitative and quantitative assessment of tumor hypoxia. |
M7924 | Metergoline | Antagonist at 5-HT1, 5-HT2, and 5-HT7 serotonin receptors; analgesic; antipyretic. |
M7887 | α-Linolenic acid | An ω-3 fatty acid that serves as a precursor to eicosapentaenoic acid (EPA) but not docosahexaenoic acid. |
M7873 | Kynurenic acid | Kynurenic acid is a non-selective antagonist at NMDA and AMPA/kainate receptors; blocks kainic acid neurotoxicity. |
M7867 | JNJ-10198409 | JNJ-10198409 is a potent ATP-competitive inhibitor of Platelet-Derived Growth Factor receptor tyrosine kinase (PDGF-RTK) with both antiangiogenic and a direct tumor cell antiproliferative activity. |
M7829 | 6β-Hydroxytestosterone | 6β-Hydroxytestosterone is a CYP3A4 metabolite; androgenic. |
M7820 | GW8510 | GW8510 is an inhibitor of cyclin kinase 2 (CDK2). |
M7804 | 5-Fluoro-2′-deoxycytidine | 5-Fluoro-2′-deoxycytidine is a mechanism based DNMT (DNA cytosine-5 methyltransferase) inhibitor, that forms a covalent link with the cysteine residue in the active site of DNMT. |
M7802 | Fadrozole hydrochloride | Fadrozole is a nonsteroidal aromatase inhibitor. |
M7773 | dPPA | Selective activator of PKC beta. |
M7761 | Diacylglycerol Kinase Inhibitor II | Diacylglycerol kinase inhibitor. |
M7758 | 1,7-Dimethylxanthine | Adenosine receptor ligand; major metabolite of caffeine. |
M7746 | Dexrazoxane | Dexrazoxane (ICRF-187, ADR-529, DXZ) is an iron chelator that can be used to prevent DOX-induced cardiotoxicity. |
M7741 | DNQX | DNQX is a competitive kainate, quisqualate (non-NMDA) glutamate receptor antagonist. |
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