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Cucurbitadienol

Cat. No. M10903

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Cucurbitadienol Structure
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5mg USD 1240  USD1240 In stock
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Biological Activity

Cucurbitadienol has significant anti-inflammatory, anti-tumor effect, is also CucurbitacinBE compounds biosynthesis the key intermediate. Cucurbitadienol synthase, the first committed enzyme for cucurbitacin biosynthesis, is a distinct enzyme from cycloartenol synthase for phytosterol biosynthesis. CYP87D18 catalyzed the oxidation of cucurbitadienol at C-11 to produce 11-oxo cucurbitadienol and 11-hydroxy cucurbitadienol.

Chemical Information
Molecular Weight 426.72
Formula C30H50O
CAS Number 35012-08-9
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Jing Qiao, et al. Molecules. Identification of a Novel Specific Cucurbitadienol Synthase Allele in Siraitia grosvenorii Correlates with High Catalytic Efficiency

[2] Jing Qiao, et al. J Ind Microbiol Biotechnol. Modification of isoprene synthesis to enable production of curcurbitadienol synthesis in Saccharomyces cerevisiae

[3] Shou-Lian Li, et al. Zhongguo Zhong Yao Za Zhi. [Study of heterologous efficient synthesis of cucurbitadienol]

[4] Jiangsheng Zhang, et al. Plant Cell Physiol. Oxidation of Cucurbitadienol Catalyzed by CYP87D18 in the Biosynthesis of Mogrosides from Siraitia grosvenorii

[5] Longhai Dai, et al. Plant Cell Physiol. Functional Characterization of Cucurbitadienol Synthase and Triterpene Glycosyltransferase Involved in Biosynthesis of Mogrosides from Siraitia grosvenorii

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Keywords: Cucurbitadienol supplier, inhibitors, activators

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