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Tentoxin

Cat. No. M10544
Tentoxin Structure
Size Price Availability Quantity
1mg USD 1500  USD1500 In stock
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Quality Control
  • Current batch:
  • Purity >95%
  • COA
  • MSDS
Biological Activity

Tentoxin is a cyclic tetrapeptide isolated from Alternaria tenuis, acts as a herbicide, causes seedling chlorosis, inhibits cyclic photophosphorylation and functions as an energy transfer inhibitor.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

Chemical Information
Molecular Weight 414.5
Formula C22H30N4O4
CAS Number 28540-82-1
Purity >95%
Solubility
Storage 2-8°C, dry, sealed
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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: Tentoxin supplier, inhibitors

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