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BI-9321 trihydrochloride is a potent, selective, cell-active NSD3-PWWP1 antagonist,Kd The value is 166 nM. BI-9321 is not valid for NSD2-PWWP1 and NSD3-PWWP2. BI-9321 trihydrochloride specifically disrupts NSD3-PWWP1 interaction with histones in U2OS cells,IC50 1.2 μM.
| Molecular Weight | 396.89 |
| Formula | C22H22ClFN4 |
| CAS Number | 2387510-87-2 |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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