Certificate of Analysis
| Product Name: | BI-9321 trihydrochloride |
| Catalog Number: | M10797 |
| CAS Number: | 2387510-87-2 |
Physical and Chemical Properties
| Formula: | C22H22ClFN4 |
| Molecular Weight: | 396.89 |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | >98% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | BI-9321 trihydrochloride is a potent, selective, cell-active NSD3-PWWP1 antagonist,Kd The value is 166 nM. BI-9321 is not valid for NSD2-PWWP1 and NSD3-PWWP2. BI-9321 trihydrochloride specifically disrupts NSD3-PWWP1 interaction with histones in U2OS cells,IC50 1.2 μM. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |