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GNF-6231

Cat. No. M10823

All AbMole products are for research use only, cannot be used for human consumption.

GNF-6231  Structure
Size Price Availability Quantity
5mg USD 70 In stock
10mg USD 115 In stock
25mg USD 200 In stock
50mg USD 310 In stock
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Quality Control & Documentation
Biological Activity

GNF-6231 is a strong, selective, oral-capable Porcupine inhibitor capable of blocking the Wnt signaling pathway.

Chemical Information
Molecular Weight 448.49
Formula C24H25FN6O2
CAS Number 1243245-18-2
Solubility (25°C) DMSO ≥ 20 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Dikshya Bastakoty, et al. Cell Stem Cells Regen Med. Temporary, Systemic Inhibition of the WNT/β-Catenin Pathway promotes Regenerative Cardiac Repair following Myocardial Infarct

[2] Dai Cheng, et al. ACS Med Chem Lett. Discovery of Pyridinyl Acetamide Derivatives as Potent, Selective, and Orally Bioavailable Porcupine Inhibitors

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Keywords: GNF-6231 supplier, inhibitors, activators

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