Catalog

Nrf2 Nuclear factor (erythroid-derived 2)-like 2

Inhibitors

Cat.No.	Name	Information
M10081	Omaveloxolone	Omaveloxolone (RTA-408) is a member of the synthetic oleanane triterpenoid class of compounds and an activator of nuclear factor erythroid 2 [NF-E2]-related factor 2 (Nrf2).
M9604	Kinsenoside	Kinsenoside is a main active component isolated from plants of the genus Anoectochilus, and exhibits many biological activities and pharmacological effects.
M9225	4-Octyl Itaconate	4-Octyl Itaconate is a cell-permeable anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1.
M9140	Hinokitiol	Hinokitiol (β-thujaplicin) is a component of essential oils isolated from Chymacyparis obtusa, reduces Nrf2 expression, and decreases DNMT1 and UHRF1 mRNA and protein expression, with anti-infective, anti-oxidative, and anti-tumor activities.
M8710	Brusatol	Brusatol (Brutasol) is a plant-derived natural quassinoid that exhibits broad cytotoxicity in cancer cultures (IC₅₀<1 μM against 457 cancer cell lines) by inhibiting de novo synthesis of cellular proteins (Effective conc.
M8692	ML385	ML385 inihbits the activity of the Nrf2 transcription factor by binding to Neh1, a CNC-bZIP domain that allows Nrf2 to heterodimerize with small Maf proteins, blocking NRF2 transcriptional activity.
M8404	Danshensu	Danshensu is an active component of Salvia miltiorrhiza (Danshen) that suppresses the formation of reactive oxygen species, inhibits platelet adhesion and aggregation, and protects myocardium against ischemia.