L-Sulforaphane is a highly potent inducer of the Keap1/Nrf2/ARE pathway.
| Molecular Weight | 177.29 |
| Formula | C6H11NOS2 |
| CAS Number | 142825-10-3 |
| Form | Liquid |
| Solubility (25°C) | DMSO 90 mg/mL |
| Storage | -20°C, protect from light |
| Species | Mouse | Rat | Rabbit | Guinea pig | Hamster | Dog |
| Weight (kg) | 0.02 | 0.15 | 1.8 | 0.4 | 0.08 | 10 |
| Body Surface Area (m2) | 0.007 | 0.025 | 0.15 | 0.05 | 0.02 | 0.5 |
| Km factor | 3 | 6 | 12 | 8 | 5 | 20 |
| Animal A (mg/kg) = Animal B (mg/kg) multiplied by | Animal B Km |
| Animal A Km |
For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.
| Related Keap1-Nrf2 Products |
|---|
| TAT-14
TAT-14 is a 14-mer peptide that acts as Nrf2 activator with an anti-inflammatory effect. |
| [D-Asp3]-Microcystin-LR
Microcystin-[D-Asp3]-LR/Microcystin A is a cyanotoxin. |
| Keap1-Nrf2 probe
Keap1-Nrf2 probe is a fluorescent Keap1-Nrf2 probe. |
| BAY-3605349
BAY-3605349 is an orally active Kelch-like ECH-associated protein 1 (KEAP1) activator as well as Nrf2 inhibitor for tumor-related studies. |
| Nrf2/HO-1 activator 1
Nrf2/HO-1 activator 1 is a potent Nrf2/HO-1 activator, neuroprotective agent. |
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2023 AbMole BioScience. All Rights Reserved.
