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Brusatol (Brutasol) is a plant-derived natural quassinoid that exhibits broad cytotoxicity in cancer cultures (IC50 <1 μM against 457 cancer cell lines) by inhibiting de novo synthesis of cellular proteins (Effective conc. <50 nM in A549 cells), including NRF2.
Cytokine. 2023 Oct 3;172:156375.
Thymoquinone attenuates inflammation in C. Albicans keratitis by activating Nrf2/HO-1 signaling pathway and reducing fungal load
Brusatol purchased from AbMole
| Molecular Weight | 520.53 |
| Formula | C26H32O11 |
| CAS Number | 14907-98-3 |
| Solubility (25°C) | DMSO 16 mg/mL (warmed) |
| Storage | 2-8°C, protect from light, sealed |
[4] Sabrina J Cai, et al. Brusatol, an NRF2 inhibitor for future cancer therapeutic
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Products are for research use only. Not for human use. We do not sell to patients.
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