| Cat.No. | Name | Information |
|---|---|---|
| M3621 | Ionomycin | Ionomycin is a calcium ionophor and an antibiotic produced by Streptomyces conglobatus. |
| M3807 | Ionomycin (Calcium salt) | Ionomycin is a calcium ionophor and an antibiotic produced by Streptomyces conglobatus. |
| M7409 | Thapsigargin | Thapsigargin is an endoplasmic reticulum (ER) stress inducer, it is also an inhibitor of microsomal Ca2+-ATPase. |
| M5073 | (R)-(+)-BAY K 8644 | (R)-(+)-BAY K 8644 is a calcium channel inhibitor, inhibits Ba2+ currents (IBa) with IC50 of 975 nM. |
| M3424 | Nifedipine | Nifedipine (BAY-a-1040) is a potent vasodilator agent with calcium antagonistic action. |
| M14204 | Verapamil | Verapamil ((±)-Verapamil) is a calcium channel blocker and a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor. |
| M3956 | Ranolazine dihydrochloride | Ranolazine (CVT 303) is an anti-angina and anti-ischemia agent that works by inhibiting the late effects of inward sodium current (IC50 values of 6 μM and 12 μM for INa and IKr, respectively) without affecting heart rate or blood pressure. Ranolazine is also a partial inhibitor of fatty acid oxidation (FAO). |
| M3613 | NP118809 | NP-118809 (39-1B4) is a potent N-type calcium channel blockers (IC50= 0.11 uM) ; good selectivity over L-type calcium channels. |
| M3572 | Manidipine | Manidipine is a lipophilic, third-generation, highly vasoselective dihydropyridine calcium antagonist with an IC50 of 2.6 nM. |
| M3500 | Diltiazem hydrochloride | Diltiazem hydrochloride is a calcium channel blocker that inhibits the transmembrane influx of extracellular calcium ions. Diltiazem hydrochloride is used in studies related to tumor and cardiovascular diseases. |
| M3498 | Nimodipine | Nimodipine is an orally active, well-tolerated and light-sensitive dihydropyridine calcium antagonist and an analogue of the calcium channel blocker nifedipine, with antihypertensive activity.Nimodipine decreases intracellular free Ca2+,Beclin-1 and autophagy. |
| M3462 | Nisoldipine | Nisoldipine (Sular) is a calcium channel blocker belonging to the dihydropyridines class, specific for L-type Cav1.2 with IC50 of 10 nM. |
| M3455 | Nitrendipine | Nitrendipine is a dihydropyridine calcium channel blocker with an IC50 of 95 nM. |
| M3440 | Nilvadipine | Nilvadipine is a potent calcium channel blocker with an IC50 of 0.03 nM. |
| M3365 | Tetracaine hydrochloride | Tetracaine hydrochloride is a hydrochloride salt form of tetracaine which is a potent local anaesthetic and a channel function allosteric inhibitor. |
| M3345 | Primidone | Primidone is an anticonvulsant of the pyrimidinedione class. Primidone is a neuronal voltage-gated sodium channel (VGSC) blocker and can be used for the study of epilepsy, essential tremor, and Psychiatric disorders. |
| M3296 | Manidipine dihydrochloride | Manidipine dihydrochloride is a hydrochloride salt form of Manidipine, which is a calcium channel blocker with IC50 of 2.6 nM, used clinically as an antihypertensive. Phase 4. |
| M3210 | Benidipine hydrochloride | Benidipine hydrochloride is a hydrochloride salt form of benidipine which is a dihydropyridine calcium channel blocker. |
| M3118 | Verapamil hydrochloride | Verapamil hydrochloride (VPH) is an orally active L-type calcium channel inhibitor that eliminates calcium channel agonist-induced calcium inward flow and apoptosis. Verapamil hydrochloride is a calcium channel blocker and a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor. |
| M2921 | Penfluridol | Penfluridol is a highly potent, first generation diphenylbutylpiperidine antipsychotic. |
| M2881 | Nicardipine hydrochloride | Nicardipine is a dihydropyridine calcium-channel blocking agent used for the treatment of vascular disorders. |
| M2820 | Lomerizine dihydrochloride | Lomerizine dihydrochloride is a relatively new L- and T-type calcium channel blocker used in the treatment of migraine. |
| M2520 | Cinepazide maleate | Cinepazide maleate is a maleate salt form of cinepazide which is a vasodilator. |
| M2496 | Catharanthine | Catharanthine inhibits nicotinic receptor mediated diaphragm contractions with IC50 of 59.6 μM |
| M2425 | Azelnidipine | Azelnidipine is a novel dihydropyridine derivative, a L-type calcium channel blocker, and an antihypertensive. Azelnidipine inhibits the intracellular calcium ion flow and lower blood pressure by selectively blocking L-type calcium channel on the membrane of vascular smooth muscle. Azelnidipine inhibits esophageal squamous cell carcinoma proliferation by targeting MEK1/2. Azelnidipine also has anti-inflammatory, antioxidant and neuroprotective effects. |
| M2248 | Cilnidipine | Cilnidipine is a dual L- and N-type calcium channel blocker that displays antihypertensive, sympatholytic and neuroprotective activity. |
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