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Calcium Channel Calcium Channel

Cat.No.  Name Information
M3621 Ionomycin Ionomycin is a calcium ionophor and an antibiotic produced by Streptomyces conglobatus.
M3807 Ionomycin (Calcium salt) Ionomycin is a calcium ionophor and an antibiotic produced by Streptomyces conglobatus.
M7409 Thapsigargin Thapsigargin is an endoplasmic reticulum (ER) stress inducer, it is also an inhibitor of microsomal Ca2+-ATPase.
M5073 (R)-(+)-BAY K 8644 (R)-(+)-BAY K 8644 is a calcium channel inhibitor, inhibits Ba2+ currents (IBa) with IC50 of 975 nM.
M3424 Nifedipine Nifedipine (BAY-a-1040) is a potent vasodilator agent with calcium antagonistic action.
M14204 Verapamil Verapamil ((±)-Verapamil) is a calcium channel blocker and a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor.
M27682 JTV-519 JTV-519 (K201) is a Ca2+-dependent blocker of sarcoplasmic reticulum Ca2+-stimulated ATPase (SERCA) and a partial agonist of ryanodine receptors in striated muscle. Antiarrhythmic and cardioprotective properties.
M22480 8-Bromo-cGMP sodium 8-Bromo-cGMP sodium is a PKG (protein kinase G) activator, it is a membrane-permeable analogue of cGMP. 8-Bromo-cGMP sodium significantly inhibits Ca2+ macroscopic currents and impairs insulin release stimulated with high K+.
M21839 ABT-639 hydrochloride ABT-639 hydrochloride is a novel selective T-type Ca2+ channel blocker.
M21786 ACT-709478 ACT-709478 is a selective, orally active and brain-penetrating T-type calcium channel blocker (Cav3.1, Cav 3.2, Cav 3.3).
M21118 HSK16149 HSK16149 is an oral γ-aminobutyric acid analog and a novel voltage-gated calcium channel (VGCC) α2δ subunit ligand for studies related to diabetic peripheral neuralgia (DPNP).
M20983 Barnidipine Barnidipine (Libradin, Mepirodipine, Vasexten, YM-09730-5, Cyress, Hypoca, Oldeca) is an antihypertensive drug that belongs to the dihydropyridine (DHP) group of calcium antagonist (CaA) with Ki of 0.21 nM for [3H]nitrendipine binding sites.
M20974 Pranidipine Pranidipine is a new 1,4-dihydropyridine calcium channel blocker. Pranidipine can enhance cyclic GMP-independent nitric oxide-induced relaxation of the rat aorta.
M20928 Lanthanum(III) chloride heptahydrate Lanthanum(III) chloride is the inorganic compound used in biochemical research to block the activity of divalent cation channels, mainly calcium channels.
M20576 Pinaverium bromide Pinaverium bromide acts as a calcium channel blocker and is useful for functional gastrointestinal disorders.
M20415 DHBP dibromide DHBP, a viologen for electrochromic memory display agent, inhibits the calcium release induced by 2 mM caffeine and 2 μg/ml polylysine with an IC50 value of 5 μg/ml and 4 μg/ml respectively.
M20409 Levamlodipine Levamlodipine is a pharmacologically active enantiomer of amlodipine which belongs to the dihydropyridine group of calcium channel blocker. It acts on the L-type of calcium channels and its treatment results in vasodilation and a fall in blood pressure.
M19149 Denudatin B (-)-Denudatin B is an antiplatelet agent. (-)-Denudatin B relaxed vascular smooth muscle by inhibiting the Ca2+ influx through voltage-gated and receptor-operated Ca2+ channels. And (-)-Denudatin B has nonspecific antiplatelet action
M18752 Praeruptorin C Praeruptorin C is a calcium antagonist.
M14203 Norverapamil hydrochloride Norverapamil hydrochloride ((±)-Norverapamil hydrochloride), an N-demethylated metabolite of Verapamil, is a L-type calcium channel blocker and a P-glycoprotein (P-gp) function inhibitor.
M14202 NecroX-5 NecroX-5 is a derivative of the NecroX, reduces intracellular calcium concentration, and possesses anti-inflammatory and anti-cancer activity.
M14195 Dehydronitrosonisoldipine Dehydronitrosonisoldipine is a calcium channel antagonist.
M14193 Cav 2.2 blocker 1 Cav 2.2 blocker 1 (compound 9) is a N-type calcium channel (Cav 2.2) blocker for the treatment of pain, with an IC50 of 1 nM.
M7906 MRS1845 MRS1845 is a selective store-operated calcium (SOC) channel inhibitor with an IC50 of 1.7 μM.
M7796 Fluspirilene Fluspirilene is a non-competitive L-type calcium channel antagonist (IC50 = 0.03μM). It is also a dopamine receptor antagonist and can be used as a precursor structure for the development of 20S proteasome agonists.




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