Cat.No. | Name | Information |
---|---|---|
M3621 | Ionomycin | Ionomycin is a calcium ionophor and an antibiotic produced by Streptomyces conglobatus. |
M3807 | Ionomycin (Calcium salt) | Ionomycin is a calcium ionophor and an antibiotic produced by Streptomyces conglobatus. |
M7409 | Thapsigargin | Thapsigargin is an endoplasmic reticulum (ER) stress inducer, it is also an inhibitor of microsomal Ca2+-ATPase. |
M5073 | (R)-(+)-BAY K 8644 | (R)-(+)-BAY K 8644 is a calcium channel inhibitor, inhibits Ba2+ currents (IBa) with IC50 of 975 nM. |
M3424 | Nifedipine | Nifedipine (BAY-a-1040) is a potent vasodilator agent with calcium antagonistic action. |
M14204 | Verapamil | Verapamil ((±)-Verapamil) is a calcium channel blocker and a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor. |
M27682 | JTV-519 | JTV-519 (K201) is a Ca2+-dependent blocker of sarcoplasmic reticulum Ca2+-stimulated ATPase (SERCA) and a partial agonist of ryanodine receptors in striated muscle. Antiarrhythmic and cardioprotective properties. |
M22480 | 8-Bromo-cGMP sodium | 8-Bromo-cGMP sodium is a PKG (protein kinase G) activator, it is a membrane-permeable analogue of cGMP. 8-Bromo-cGMP sodium significantly inhibits Ca2+ macroscopic currents and impairs insulin release stimulated with high K+. |
M21839 | ABT-639 hydrochloride | ABT-639 hydrochloride is a novel selective T-type Ca2+ channel blocker. |
M21786 | ACT-709478 | ACT-709478 is a selective, orally active and brain-penetrating T-type calcium channel blocker (Cav3.1, Cav 3.2, Cav 3.3). |
M21118 | HSK16149 | HSK16149 is an oral γ-aminobutyric acid analog and a novel voltage-gated calcium channel (VGCC) α2δ subunit ligand for studies related to diabetic peripheral neuralgia (DPNP). |
M20983 | Barnidipine | Barnidipine (Libradin, Mepirodipine, Vasexten, YM-09730-5, Cyress, Hypoca, Oldeca) is an antihypertensive drug that belongs to the dihydropyridine (DHP) group of calcium antagonist (CaA) with Ki of 0.21 nM for [3H]nitrendipine binding sites. |
M20974 | Pranidipine | Pranidipine is a new 1,4-dihydropyridine calcium channel blocker. Pranidipine can enhance cyclic GMP-independent nitric oxide-induced relaxation of the rat aorta. |
M20928 | Lanthanum(III) chloride heptahydrate | Lanthanum(III) chloride is the inorganic compound used in biochemical research to block the activity of divalent cation channels, mainly calcium channels. |
M20576 | Pinaverium bromide | Pinaverium bromide acts as a calcium channel blocker and is useful for functional gastrointestinal disorders. |
M20415 | DHBP dibromide | DHBP, a viologen for electrochromic memory display agent, inhibits the calcium release induced by 2 mM caffeine and 2 μg/ml polylysine with an IC50 value of 5 μg/ml and 4 μg/ml respectively. |
M20409 | Levamlodipine | Levamlodipine is a pharmacologically active enantiomer of amlodipine which belongs to the dihydropyridine group of calcium channel blocker. It acts on the L-type of calcium channels and its treatment results in vasodilation and a fall in blood pressure. |
M19149 | Denudatin B | (-)-Denudatin B is an antiplatelet agent. (-)-Denudatin B relaxed vascular smooth muscle by inhibiting the Ca2+ influx through voltage-gated and receptor-operated Ca2+ channels. And (-)-Denudatin B has nonspecific antiplatelet action |
M18752 | Praeruptorin C | Praeruptorin C is a calcium antagonist. |
M14203 | Norverapamil hydrochloride | Norverapamil hydrochloride ((±)-Norverapamil hydrochloride), an N-demethylated metabolite of Verapamil, is a L-type calcium channel blocker and a P-glycoprotein (P-gp) function inhibitor. |
M14202 | NecroX-5 | NecroX-5 is a derivative of the NecroX, reduces intracellular calcium concentration, and possesses anti-inflammatory and anti-cancer activity. |
M14195 | Dehydronitrosonisoldipine | Dehydronitrosonisoldipine is a calcium channel antagonist. |
M14193 | Cav 2.2 blocker 1 | Cav 2.2 blocker 1 (compound 9) is a N-type calcium channel (Cav 2.2) blocker for the treatment of pain, with an IC50 of 1 nM. |
M7906 | MRS1845 | MRS1845 is a selective store-operated calcium (SOC) channel inhibitor with an IC50 of 1.7 μM. |
M7796 | Fluspirilene | Fluspirilene is a non-competitive L-type calcium channel antagonist (IC50 = 0.03μM). It is also a dopamine receptor antagonist and can be used as a precursor structure for the development of 20S proteasome agonists. |
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