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Calcium Channel Calcium Channel

Cat.No.  Name Information
M3621 Ionomycin Ionomycin is a calcium ionophor and an antibiotic produced by Streptomyces conglobatus.
M3807 Ionomycin (Calcium salt) Ionomycin is a calcium ionophor and an antibiotic produced by Streptomyces conglobatus.
M7409 Thapsigargin Thapsigargin is an endoplasmic reticulum (ER) stress inducer, it is also an inhibitor of microsomal Ca2+-ATPase.
M5073 (R)-(+)-BAY K 8644 (R)-(+)-BAY K 8644 is a calcium channel inhibitor, inhibits Ba2+ currents (IBa) with IC50 of 975 nM.
M3424 Nifedipine Nifedipine (BAY-a-1040) is a potent vasodilator agent with calcium antagonistic action.
M14204 Verapamil Verapamil ((±)-Verapamil) is a calcium channel blocker and a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor.
M3462 Nisoldipine Nisoldipine (Sular) is a calcium channel blocker belonging to the dihydropyridines class, specific for L-type Cav1.2 with IC50 of 10 nM.
M3455 Nitrendipine Nitrendipine is a dihydropyridine calcium channel blocker with an IC50 of 95 nM.
M3440 Nilvadipine Nilvadipine is a potent calcium channel blocker with an IC50 of 0.03 nM.
M3424 Nifedipine Nifedipine (BAY-a-1040) is a potent vasodilator agent with calcium antagonistic action.
M3365 Tetracaine hydrochloride Tetracaine hydrochloride is a hydrochloride salt form of tetracaine which is a potent local anaesthetic and a channel function allosteric inhibitor.
M3345 Primidone Primidone is an anticonvulsant of the pyrimidinedione class. Primidone is a neuronal voltage-gated sodium channel (VGSC) blocker and can be used for the study of epilepsy, essential tremor, and Psychiatric disorders.
M3296 Manidipine dihydrochloride Manidipine dihydrochloride is a hydrochloride salt form of Manidipine, which is a calcium channel blocker with IC50 of 2.6 nM, used clinically as an antihypertensive. Phase 4.
M3210 Benidipine hydrochloride Benidipine hydrochloride is a hydrochloride salt form of benidipine which is a dihydropyridine calcium channel blocker.
M3118 Verapamil hydrochloride Verapamil hydrochloride (VPH) is an orally active L-type calcium channel inhibitor that eliminates calcium channel agonist-induced calcium inward flow and apoptosis. Verapamil hydrochloride is a calcium channel blocker and a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor.
M2921 Penfluridol Penfluridol is a highly potent, first generation diphenylbutylpiperidine antipsychotic.
M2881 Nicardipine hydrochloride Nicardipine is a dihydropyridine calcium-channel blocking agent used for the treatment of vascular disorders.
M2820 Lomerizine dihydrochloride Lomerizine dihydrochloride is a relatively new L- and T-type calcium channel blocker used in the treatment of migraine.
M2520 Cinepazide maleate Cinepazide maleate is a maleate salt form of cinepazide which is a vasodilator.
M2496 Catharanthine Catharanthine inhibits nicotinic receptor mediated diaphragm contractions with IC50 of 59.6 μM
M2425 Azelnidipine Azelnidipine is a novel dihydropyridine derivative, a L-type calcium channel blocker, and an antihypertensive. Azelnidipine inhibits the intracellular calcium ion flow and lower blood pressure by selectively blocking L-type calcium channel on the membrane of vascular smooth muscle. Azelnidipine inhibits esophageal squamous cell carcinoma proliferation by targeting MEK1/2. Azelnidipine also has anti-inflammatory, antioxidant and neuroprotective effects.
M2248 Cilnidipine Cilnidipine is a dual L- and N-type calcium channel blocker that displays antihypertensive, sympatholytic and neuroprotective activity.
M1927 KB-R7943 mesylate KB-R7943 mesylate is a potent, selective inhibitor of the reverse mode of the Na+/Ca2+ exchanger (IC50 = 0.7 mM).
M56458 TTA-A8  TTA-A8 is a short-acting T-type calcium channel antagonist with oral activity, exhibiting an IC50 value of 31.3 nM in the FLIPR depolarization assay.
M56457 MONIRO-1  MONIRO-1 is a T-type and N-type calcium channel blocker with IC50 values of 34, 3.3, 1.7 and 7.2 µM against hCav2.2, hCav3.1, hCav3.2 and hCav3.3, respectively.
M56456 Azumolene Azumolene (EU4093 free base), a Dantrolene analog, is a muscle relaxant.




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