Cat.No. | Name | Information |
---|---|---|
M3621 | Ionomycin | Ionomycin is a calcium ionophor and an antibiotic produced by Streptomyces conglobatus. |
M3807 | Ionomycin (Calcium salt) | Ionomycin is a calcium ionophor and an antibiotic produced by Streptomyces conglobatus. |
M7409 | Thapsigargin | Thapsigargin is an endoplasmic reticulum (ER) stress inducer, it is also an inhibitor of microsomal Ca2+-ATPase. |
M5073 | (R)-(+)-BAY K 8644 | (R)-(+)-BAY K 8644 is a calcium channel inhibitor, inhibits Ba2+ currents (IBa) with IC50 of 975 nM. |
M3424 | Nifedipine | Nifedipine (BAY-a-1040) is a potent vasodilator agent with calcium antagonistic action. |
M14204 | Verapamil | Verapamil ((±)-Verapamil) is a calcium channel blocker and a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor. |
M8859 | Xestospongin C | Xestospongin C is a selective, reversible and membrane-permeable inhibitor of IP3 receptor. |
M8747 | Synta66 | Synta66 (S66) is a CRAC (Ca2+ release-activated Ca2+) channel inhibitor that blocks SOCE (store-operated Ca2+ entry) upon Ca2+ depletion from intracellular stores by thapsigargin in human vascular smooth muscle cells (VSMCs) with high potency (IC50 = 26 nM & 43 nM based on maximum Ca2+ level & rate of increase, respectly). |
M7778 | Dantrolene sodium salt | Inhibitor of Ca2+ release from sarcoplasmic reticulum; muscle relaxant. |
M7106 | PD 173212 | PD 173212 is a potent N-type voltage-gated calcium channel blocker (IC50 = 36 nM). |
M7034 | NNC 55-0396 dihydrochloride | NNC 55-0396 dihydrochloride is a highly selective Ca 2+ channel blocker (T-type). |
M6499 | Bepridil hydrochloride | Bepridil hydrochloride (CERM 1978) is a calcium channel blocker, with antianginal activity. |
M6185 | YM-58483 | YM-58483 is the first selective and potent inhibitor of CRAC channels and subsequent Ca2+ signals. |
M6124 | Wilforgine | TwMDR1 transports sesquiterpene pyridine alkaloids, wilforine and wilforgine, into the hairy roots of T. wilfordii Hook.f. resulting in low secretion ratio of alkaloids. |
M6092 | Mirogabalin | Mirogabalin (DS-5565) is a novel, preferentially selective α2δ-1 ligand characterized by high potency and selectivity to the α2δ-1 subunit of voltage-sensitive calcium-channel complexes in the CNS. |
M6038 | Trimethadione | Trimethadione is an oxazolidinedione anticonvulsant; commonly used to treat epileptic conditions. |
M5922 | Ranolazine | Ranolazine (CVT 303) is an anti-angina and anti-ischemia agent that works by inhibiting the late effects of inward sodium current (IC50 values of 6 μM and 12 μM for INa and IKr, respectively) without affecting heart rate or blood pressure. Ranolazine is also a partial inhibitor of fatty acid oxidation (FAO). |
M5756 | L-Phenylalanine | L-Phenylalanine is an antagonist at α2δ calcium channels with a Ki of 980 nM. |
M5738 | Levosimendan | Levosimendan is a calcium sensitizer acting through calcium-dependent binding to cardiac troponin C (cTnC), provides treatment for heart failure. |
M5733 | Lercanidipine hydrochloride | Lercanidipine hydrochloride is a calcium channel blocker of the dihydropyridine class. |
M5723 | Lacidipine | Lacidipine is a L-type calcium channel blocker, used for treating high blood pressure. |
M5717 | Isradipine | Isradipine is a potent and selective L-type voltage-gated calcium channel blocker, used to treat high blood pressure. |
M5654 | Flunarizine 2HCl | Flunarizine 2HCl is a dihydrochloride salt form which is a calcium channel blocker with a Ki of 68 nM. Flunarizine dihydrochloride is a potent dual Na+/Ca2+ channel (T-type) blocker. Flunarizine dihydrochloride is a D2 dopamine receptor antagonist. |
M5640 | Fendiline HCl | Fendiline is a nonselective calcium channel blocker. |
M5629 | Ethosuximide | Ethosuximide is a succinimide anticonvulsant, used mainly in absence seizures; A calcium channel blocker. |
M5607 | Efonidipine hydrochloride monoethanolate | Efonidipine(NZ-105) Hcl monoethanolate is a dual T-type and L-type calcium channel blocker (CCB). |
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