Cat.No. | Name | Information |
---|---|---|
M3621 | Ionomycin | Ionomycin is a calcium ionophor and an antibiotic produced by Streptomyces conglobatus. |
M3807 | Ionomycin (Calcium salt) | Ionomycin is a calcium ionophor and an antibiotic produced by Streptomyces conglobatus. |
M7409 | Thapsigargin | Thapsigargin is an endoplasmic reticulum (ER) stress inducer, it is also an inhibitor of microsomal Ca2+-ATPase. |
M5073 | (R)-(+)-BAY K 8644 | (R)-(+)-BAY K 8644 is a calcium channel inhibitor, inhibits Ba2+ currents (IBa) with IC50 of 975 nM. |
M3424 | Nifedipine | Nifedipine (BAY-a-1040) is a potent vasodilator agent with calcium antagonistic action. |
M14204 | Verapamil | Verapamil ((±)-Verapamil) is a calcium channel blocker and a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor. |
M5550 | Dantrolene sodium hemiheptahydrate | Dantrolene sodium hemiheptahydrate ia a skeletal muscle relaxant that acts by interfering with excitation-contraction coupling in the muscle fiber. |
M5439 | Butamben | Butamben is a long-duration local anesthetic used for the treatment of chronic pain. |
M5411 | Amlodipine Besylate | Amlodipine Besylate is a long-acting calcium channel blocker, used to lower blood pressure and prevent chest pain. |
M5205 | ML204 | ML204 is a novel potent antagonist that selectively modulates native TRPC4/C5 ion channels. |
M5139 | Amlodipine | Amlodipine is a long-acting calcium channel blocker, used to lower blood pressure and prevent chest pain. |
M5080 | Efonidipine hydrochloride | Efonidipine Hcl is a dual T-type and L-type calcium channel blocker . |
M5077 | (S)-(-)-BAY K 8644 | (S)-(-)-BAY K 8644 is a Ca2+ channel activator; L-type Ca2+ channel activator. |
M5075 | GV-58 | GV-58 is a potent, selective N- and P/Q-type Ca2+ channels agonist with EC50 of 7.21/8.81 uM for N-type/P-Q-type Ca2(addition) channel; 20-fold less potent CDK inhibitor activity. |
M4514 | Tetrandrine | Tetrandrine (NSC-77037; D-tetrandrine) is a diphenylisoquinoline alkaloid that inhibits voltage-gated calcium channels (ICa) and Ca2+ -activated potassium channels. |
M4485 | (±)-Praeruptorin A | (±)-Praeruptorin A is A diesterification product of cis-lactone (CKL), and is the main active component of Peucedani Radix composed of dried Peucedanum praeruptorumDunn. |
M4349 | Catharanthine-hemitartrate | Catharanthine Tartrate is an alkaloid found in periwinces that inhibits voltage-gated L-type Ca2+ channels in a function-operated cell and has anti-tumor and blood pressure lowering activities. |
M4089 | Ginsenoside-Ro | Ginsenoside Ro (Polysciasaponin P3; Chikusetsusaponin 5; Chikusetsusaponin V) has the antiplatelet effect of Ca2+ antagonist with IC50 of 155 μM. Ginsenoside Ro decreased TXA2 production and Ginsenoside Ro also slightly decreased COX-1 and TXAS activity. |
M4076 | Ginsenoside-Rf | Ginsenoside Rf is a trace component of ginseng root. Ginsenoside Rf inhibits N-type Ca2+ channels. |
M3959 | Felodipine | Felodipine is a L-type Ca2+ channel blocker that is selective over N-, R-, P/Q- and T-type channels with IC50 of 0.15 nM. |
M3958 | Clevidipine butyrate | Clevidipine butyrate is an ultrashort-acting intravenous dihydropyridine calcium-channel blocker which is used as an agent for the reduction of blood pressure. |
M3956 | Ranolazine dihydrochloride | Ranolazine (CVT 303) is an anti-angina and anti-ischemia agent that works by inhibiting the late effects of inward sodium current (IC50 values of 6 μM and 12 μM for INa and IKr, respectively) without affecting heart rate or blood pressure. Ranolazine is also a partial inhibitor of fatty acid oxidation (FAO). |
M3613 | NP118809 | NP-118809 (39-1B4) is a potent N-type calcium channel blockers (IC50= 0.11 uM) ; good selectivity over L-type calcium channels. |
M3572 | Manidipine | Manidipine is a lipophilic, third-generation, highly vasoselective dihydropyridine calcium antagonist with an IC50 of 2.6 nM. |
M3500 | Diltiazem hydrochloride | Diltiazem hydrochloride is a calcium channel blocker that inhibits the transmembrane influx of extracellular calcium ions. Diltiazem hydrochloride is used in studies related to tumor and cardiovascular diseases. |
M3498 | Nimodipine | Nimodipine is an orally active, well-tolerated and light-sensitive dihydropyridine calcium antagonist and an analogue of the calcium channel blocker nifedipine, with antihypertensive activity.Nimodipine decreases intracellular free Ca2+,Beclin-1 and autophagy. |
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