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Calcium Channel Calcium Channel

Cat.No.  Name Information
M3621 Ionomycin Ionomycin is a calcium ionophor and an antibiotic produced by Streptomyces conglobatus.
M3807 Ionomycin (Calcium salt) Ionomycin is a calcium ionophor and an antibiotic produced by Streptomyces conglobatus.
M7409 Thapsigargin Thapsigargin is an endoplasmic reticulum (ER) stress inducer, it is also an inhibitor of microsomal Ca2+-ATPase.
M5073 (R)-(+)-BAY K 8644 (R)-(+)-BAY K 8644 is a calcium channel inhibitor, inhibits Ba2+ currents (IBa) with IC50 of 975 nM.
M3424 Nifedipine Nifedipine (BAY-a-1040) is a potent vasodilator agent with calcium antagonistic action.
M14204 Verapamil Verapamil ((±)-Verapamil) is a calcium channel blocker and a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor.
M5550 Dantrolene sodium hemiheptahydrate Dantrolene sodium hemiheptahydrate ia a skeletal muscle relaxant that acts by interfering with excitation-contraction coupling in the muscle fiber.
M5439 Butamben Butamben is a long-duration local anesthetic used for the treatment of chronic pain.
M5411 Amlodipine Besylate Amlodipine Besylate is a long-acting calcium channel blocker, used to lower blood pressure and prevent chest pain.
M5205 ML204 ML204 is a novel potent antagonist that selectively modulates native TRPC4/C5 ion channels.
M5139 Amlodipine Amlodipine is a long-acting calcium channel blocker, used to lower blood pressure and prevent chest pain.
M5080 Efonidipine hydrochloride Efonidipine Hcl is a dual T-type and L-type calcium channel blocker .
M5077 (S)-(-)-BAY K 8644 (S)-(-)-BAY K 8644 is a Ca2+ channel activator; L-type Ca2+ channel activator.
M5075 GV-58 GV-58 is a potent, selective N- and P/Q-type Ca2+ channels agonist with EC50 of 7.21/8.81 uM for N-type/P-Q-type Ca2(addition) channel; 20-fold less potent CDK inhibitor activity.
M4514 Tetrandrine Tetrandrine (NSC-77037; D-tetrandrine) is a diphenylisoquinoline alkaloid that inhibits voltage-gated calcium channels (ICa) and Ca2+ -activated potassium channels.
M4485 (±)-Praeruptorin A (±)-Praeruptorin A is A diesterification product of cis-lactone (CKL), and is the main active component of Peucedani Radix composed of dried Peucedanum praeruptorumDunn.
M4349 Catharanthine-hemitartrate Catharanthine Tartrate is an alkaloid found in periwinces that inhibits voltage-gated L-type Ca2+ channels in a function-operated cell and has anti-tumor and blood pressure lowering activities.
M4089 Ginsenoside-Ro Ginsenoside Ro (Polysciasaponin P3; Chikusetsusaponin 5; Chikusetsusaponin V) has the antiplatelet effect of Ca2+ antagonist with IC50 of 155 μM. Ginsenoside Ro decreased TXA2 production and Ginsenoside Ro also slightly decreased COX-1 and TXAS activity.
M4076 Ginsenoside-Rf Ginsenoside Rf is a trace component of ginseng root. Ginsenoside Rf inhibits N-type Ca2+ channels.
M3959 Felodipine Felodipine is a L-type Ca2+ channel blocker that is selective over N-, R-, P/Q- and T-type channels with IC50 of 0.15 nM.
M3958 Clevidipine butyrate Clevidipine butyrate is an ultrashort-acting intravenous dihydropyridine calcium-channel blocker which is used as an agent for the reduction of blood pressure.
M3956 Ranolazine dihydrochloride Ranolazine (CVT 303) is an anti-angina and anti-ischemia agent that works by inhibiting the late effects of inward sodium current (IC50 values of 6 μM and 12 μM for INa and IKr, respectively) without affecting heart rate or blood pressure. Ranolazine is also a partial inhibitor of fatty acid oxidation (FAO).
M3613 NP118809 NP-118809 (39-1B4) is a potent N-type calcium channel blockers (IC50= 0.11 uM) ; good selectivity over L-type calcium channels.
M3572 Manidipine Manidipine is a lipophilic, third-generation, highly vasoselective dihydropyridine calcium antagonist with an IC50 of 2.6 nM.
M3500 Diltiazem hydrochloride Diltiazem hydrochloride is a calcium channel blocker that inhibits the transmembrane influx of extracellular calcium ions. Diltiazem hydrochloride is used in studies related to tumor and cardiovascular diseases.
M3498 Nimodipine Nimodipine is an orally active, well-tolerated and light-sensitive dihydropyridine calcium antagonist and an analogue of the calcium channel blocker nifedipine, with antihypertensive activity.Nimodipine decreases intracellular free Ca2+,Beclin-1 and autophagy.




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