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Calcium Channel Calcium Channel

Cat.No.  Name Information
M3621 Ionomycin Ionomycin is a calcium ionophor and an antibiotic produced by Streptomyces conglobatus.
M3807 Ionomycin (Calcium salt) Ionomycin is a calcium ionophor and an antibiotic produced by Streptomyces conglobatus.
M7409 Thapsigargin Thapsigargin is an endoplasmic reticulum (ER) stress inducer, it is also an inhibitor of microsomal Ca2+-ATPase.
M5073 (R)-(+)-BAY K 8644 (R)-(+)-BAY K 8644 is a calcium channel inhibitor, inhibits Ba2+ currents (IBa) with IC50 of 975 nM.
M3424 Nifedipine Nifedipine (BAY-a-1040) is a potent vasodilator agent with calcium antagonistic action.
M14204 Verapamil Verapamil ((±)-Verapamil) is a calcium channel blocker and a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor.
M21496 N106 N106 is a first-in-class SERCA2a SUMOylation activator of sarcoplasmic reticulum calcium ATPase (N106). N106 directly activates the SUMO activating enzyme E1 ligase. N106 can be used in heart failure research.
M20576 Pinaverium bromide Pinaverium bromide acts as a calcium channel blocker and is useful for functional gastrointestinal disorders.
M20441 Efonidipine Efonidipine is an L- and T-type calcium channel blocker leading to vasodilation and decreased automaticity of the heart. It also suppresses aldosterone secretion from the adrenal.
M20409 Levamlodipine Levamlodipine is a pharmacologically active enantiomer of amlodipine which belongs to the dihydropyridine group of calcium channel blocker. It acts on the L-type of calcium channels and its treatment results in vasodilation and a fall in blood pressure.
M19190 Cycleanine Cycleanine is a potent vascular selective Calcium antagonist. Cycleanine has analgesic, muscle relaxant and anti-inflammatory activities. Cycleanine has potential for anti-ovarian cancer acting through the apoptosis pathway.
M18297 14-Deoxyandrographolide 14-Deoxyandrographolide
M14212 Tanshinone IIA sulfonate sodium Tanshinone IIA sulfonate (sodium) is a derivative of tanshinone IIA, which acts as an inhibitor of store-operated Ca2+ entry (SOCE), and is used to treat cardiovascular disorders.
M14211 GSK-5498A GSK-5498A is a selective small molecule blocker of CARC (IC50, 1 μM); inhibits mediator release from mast cells, and pro-inflammatory cytokine release from T-cells in a variety of species.
M14201 Mibefradil dihydrochloride Mibefradil dihydrochloride (Ro 40-5967 dihydrochloride) is a calcium channel blocker with moderate selectivity for T-type Ca2+ channels (IC50s of 2.7 μM and 18.6 μM for T-type and L-type currents, respectively).
M14200 Menthol Menthol is a natural analgesic compound. Menthol could cause a feeling of coolness due to stimulation of ‘cold’ receptors by inhibiting Ca++ currents of neuronal membranes.
M14198 GSK-7975A GSK-7975A is a potent and orally available CRAC channel inhibitor.
M14197 DS16570511 DS16570511 is cell-permeable inhibitor of the mitochondrial calcium uniporter, which blocks the MCU- or MICU1-dependent increase of Ca2+ influx.
M14194 Cyclopiazonic acid Cyclopiazonic acid (CPA), a neurotoxic secondary metabolite (SM) made by A. flavus, is a nanomolar inhibitor of endoplasmic reticulum calcium ATPase (Ca2+ATPase; SERCA) and a potent inducer of cell death in plants.
M14192 CALP3 CALP3, a Ca2+-like peptide, is a potent Ca2+ channel blocker that activates EF hand motifs of Ca2+-binding proteins.
M14191 Bepridil hydrochloride hydrate Bepridil hydrochloride hydrate ((±)-Bepridil hydrochloride hydrate) is a non-selective, long-acting Ca+ channel antagonist and Na+, K+ channel inhibitor, with antianginal and type I antiarrhythmic effects.
M14190 Bay K 8644 Bay K 8644, a dihydropyridine compound, is a specific L-type Ca2+ channel agonist. Bay K 8644 increases Ca2+ influx through sarcolemmal Ca2+ channels by increasing the open time of the channel.
M14189 Amlodipine maleate Amlodipine maleate is a dihydropyridine calcium channel blocker, acts as an orally active antianginal agent.
M14188 ABT-639 ABT-639 is a novel, peripherally acting, selective T-type Ca2+ channel blocker.
M14187 ω-Conotoxin GVIA TFA ω-Conotoxin GVIA TFA is an inhibitor of the N-type Ca2+ channel.
M11507 Taurolithocholic acid sodium salt Taurolithocholic acid sodium salt is an effective bile suppressor and Ca2+ agonist.




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