Cat.No. | Name | Information |
---|---|---|
M3621 | Ionomycin | Ionomycin is a calcium ionophor and an antibiotic produced by Streptomyces conglobatus. |
M3807 | Ionomycin (Calcium salt) | Ionomycin is a calcium ionophor and an antibiotic produced by Streptomyces conglobatus. |
M7409 | Thapsigargin | Thapsigargin is an endoplasmic reticulum (ER) stress inducer, it is also an inhibitor of microsomal Ca2+-ATPase. |
M5073 | (R)-(+)-BAY K 8644 | (R)-(+)-BAY K 8644 is a calcium channel inhibitor, inhibits Ba2+ currents (IBa) with IC50 of 975 nM. |
M3424 | Nifedipine | Nifedipine (BAY-a-1040) is a potent vasodilator agent with calcium antagonistic action. |
M14204 | Verapamil | Verapamil ((±)-Verapamil) is a calcium channel blocker and a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor. |
M14212 | Tanshinone IIA sulfonate sodium | Tanshinone IIA sulfonate (sodium) is a derivative of tanshinone IIA, which acts as an inhibitor of store-operated Ca2+ entry (SOCE), and is used to treat cardiovascular disorders. |
M14211 | GSK-5498A | GSK-5498A is a selective small molecule blocker of CARC (IC50, 1 μM); inhibits mediator release from mast cells, and pro-inflammatory cytokine release from T-cells in a variety of species. |
M14204 | Verapamil | Verapamil ((±)-Verapamil) is a calcium channel blocker and a potent and orally active first-generation P-glycoprotein (P-gp) inhibitor. |
M14201 | Mibefradil dihydrochloride | Mibefradil dihydrochloride (Ro 40-5967 dihydrochloride) is a calcium channel blocker with moderate selectivity for T-type Ca2+ channels (IC50s of 2.7 μM and 18.6 μM for T-type and L-type currents, respectively). |
M14200 | Menthol | Menthol is a natural analgesic compound. Menthol could cause a feeling of coolness due to stimulation of ‘cold’ receptors by inhibiting Ca++ currents of neuronal membranes. |
M14198 | GSK-7975A | GSK-7975A is a potent and orally available CRAC channel inhibitor. |
M14197 | DS16570511 | DS16570511 is cell-permeable inhibitor of the mitochondrial calcium uniporter, which blocks the MCU- or MICU1-dependent increase of Ca2+ influx. |
M14194 | Cyclopiazonic acid | Cyclopiazonic acid (CPA), a neurotoxic secondary metabolite (SM) made by A. flavus, is a nanomolar inhibitor of endoplasmic reticulum calcium ATPase (Ca2+ATPase; SERCA) and a potent inducer of cell death in plants. |
M14192 | CALP3 | CALP3, a Ca2+-like peptide, is a potent Ca2+ channel blocker that activates EF hand motifs of Ca2+-binding proteins. |
M14191 | Bepridil hydrochloride hydrate | Bepridil hydrochloride hydrate ((±)-Bepridil hydrochloride hydrate) is a non-selective, long-acting Ca+ channel antagonist and Na+, K+ channel inhibitor, with antianginal and type I antiarrhythmic effects. |
M14190 | Bay K 8644 | Bay K 8644, a dihydropyridine compound, is a specific L-type Ca2+ channel agonist. Bay K 8644 increases Ca2+ influx through sarcolemmal Ca2+ channels by increasing the open time of the channel. |
M14189 | Amlodipine maleate | Amlodipine maleate is a dihydropyridine calcium channel blocker, acts as an orally active antianginal agent. |
M14188 | ABT-639 | ABT-639 is a novel, peripherally acting, selective T-type Ca2+ channel blocker. |
M14187 | ω-Conotoxin GVIA TFA | ω-Conotoxin GVIA TFA is an inhibitor of the N-type Ca2+ channel. |
M11507 | Taurolithocholic acid sodium salt | Taurolithocholic acid sodium salt is an effective bile suppressor and Ca2+ agonist. |
M11316 | Urolithin C | Urolithin C, a polyphenol intestinal microbial metabolite of ellagic acid, is a glucose-dependent activator of insulin secretion. Urolithin C is an L-type Ca2+ channel opening agent that enhances Ca2+ influx. Urolithin C induces apoptosis and stimulates the formation of reactive oxygen species (ROS) through mitochondria mediated pathway. |
M10367 | Ruthenium red | Ruthenium red (Ammoniated ruthenium oxychloride) is a polycationic dye widely used for electron microscopy (EM) of cells, tissues and vegetative bacteria. Ruthenium red is also a L-type calcium current (ICa) blocker, blocks Ca2+ uptake and release, and voltage-sensitive Ca2+ channels. |
M9794 | Ebselen | Ebselen (SPI-1005) is a potent voltage-dependent calcium channel (VDCC) blocker. Ebselen is an inhibitor of HIV-1 capsid CTD dimerization. Ebselen can permeate the blood-brain barrier and has anti-inflammatory, antioxidant and anticancer activity |
M9720 | Aranidipine | Aranidipine (MPC1304) is a calcium channel blocker which may positively affect ambulatory blood pressure. *This compound is unstable in solutions, freshly prepared is recommended. |
M9600 | 2-Aminoethyl diphenylborinate (2-APB) | 2-Aminoethyl diphenylborinate (2-APB) is a cell-permeable inhibitor of IP3R, and regulate IP3-induced calcium release. 2-Aminoethyl diphenylborinate also inhibits the store-operated Ca2+ (SOC) channel and activates some TRP channels (V1, V2 and V3). |
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