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N106

Cat. No. M21496

All AbMole products are for research use only, cannot be used for human consumption.

N106  Structure
Size Price Availability Quantity
5mg USD 130  USD130 In stock
10mg USD 220  USD220 In stock
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Quality Control & Documentation
Biological Activity

N106 is a first-in-class SERCA2a SUMOylation activator of sarcoplasmic reticulum calcium ATPase (N106). N106 directly activates the SUMO activating enzyme E1 ligase. N106 can be used in heart failure research.

Chemical Information
Molecular Weight 354.38
Formula C17H14N4O3S
CAS Number 862974-25-2
Solubility (25°C) DMSO ≥ 40 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Weiwei Wang, et al. J Neurochem. N-glycosylation of the human neuropeptide QRFP receptor (QRFPR) is essential for ligand binding and receptor activation

[2] Nicols Garrido, et al. Urol Clin North Am. Personalized Medicine in Infertile Men

[3] Changwon Kho, et al. Nat Commun. Small-molecule activation of SERCA2a SUMOylation for the treatment of heart failure

[4] Athanasia Varsaki, et al. Mol Microbiol. Genetic and biochemical characterization of MbeA, the relaxase involved in plasmid ColE1 conjugative mobilization

[5] J A Pineda, et al. J Neurosci. Effects of locus coeruleus lesions on auditory, long-latency, event-related potentials in monkey

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Keywords: N106 supplier, Calcium Channel, inhibitors, activators

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