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Aranidipine (MPC1304) is a calcium channel blocker which may positively affect ambulatory blood pressure. Following oral administration of Aranidipine at doses of 3 and 10 mg/kg to spontaneously hypertensive rats (SHR), there are significant decreases in Bmax values for specific [3H](+)-PN 200-110 binding to myocardial membranes compared to the control values. The Bmax values at 1 h (3 mg/kg), 1 and 6 h (10 mg/kg) are significantly decreased (47.7, 48.9 and 25.8%, respectively) compared to the control values.
*This compound is unstable in solutions, freshly prepared is recommended.
| Molecular Weight | 388.37 |
| Formula | C19H20N2O7 |
| CAS Number | 86780-90-7 |
| Solubility (25°C) | DMSO ≥ 90 mg/mL |
| Storage | -20°C, dry, sealed, protect from light |
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