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ω-Conotoxin GVIA TFA

Cat. No. M14187
ω-Conotoxin GVIA TFA Structure
Size Price Availability Quantity
1mg USD 570  USD570 In stock
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Quality Control & Documentation
Biological Activity

ω-Conotoxin GVIA TFA is an inhibitor of the N-type Ca2+ channel.

Chemical Information
Molecular Weight 3151.37
Formula C120H182N38O43S6.C2HF3O2
CAS Number 106375-28-4 (free base)
Solubility (25°C) Water 90 mg/mL
Storage -20°C, dry, sealed
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

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  Catalog
Abmole Inhibitor Catalog




Keywords: ω-Conotoxin GVIA TFA supplier, Calcium Channel, inhibitors, activators


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