| Cat.No. | Name | Information |
|---|---|---|
| M9334 | Vancomycin | Vancomycin is a glycopeptide antibiotic as well as a macrocyclic compound that can be used to construct models of bronchiectasis combined with lung infections, as well as for studies related to various bacterial infectious conditions. |
| M9316 | Ceruletide | Ceruletide is a biologically active decapeptide isolated from the skin of the Australian frog Hyla caerulea, acts as a cholecystokinin receptor agonist. |
| M9314 | Brassinolide | Brassinolide is a plant steroid that promotes cell elongation and cell devision and thus regulates plant growth and development. |
| M9267 | Coelenterazine | Coelenterazine is the luciferin, the light-emitting molecule, used for monitoring reporter genes in BRET, ELISA and HTS techniques.*The compound is unstable in solutions, freshly prepared is recommended |
| M9168 | Berberine | Berberine is an alkaloid in several plants with various biological functions, including insulin-sensitizing, anti-inflammatory, and anti-oxidant activity. Berberine induces reactive oxygen species (ROS) generation and inhibits DNA topoisomerase. |
| M8807 | Perillaldehyde | Perillaldehyde inhibits BaP-induced AHR activation and ROS production, inhibits BaP/AHR-mediated release of the CCL2 chemokine, and activats the NRF2/HO1 antioxidant pathway. |
| M8710 | Brusatol | Brusatol (NSC 172924) is a plant-derived natural quassinoid that exhibits broad cytotoxicity in cancer cultures (IC50 <1 μM against 457 cancer cell lines) by inhibiting de novo synthesis of cellular proteins (Effective conc. <50 nM in A549 cells), including NRF2. |
| M7869 | Kainic acid monohydrate | Kainic acid monohydrate is an agonist at the kainate class of ionotropic glutamate receptors, which induces seizures and neurodegeneration in vivo and is used to induce experimental epilepsy in rodents and study the mechanisms of excitation-induced neuronal apoptosis. |
| M7747 | Diosgenin | Diosgenin is a plant steroid which induces apoptosis in colon cancer cell lines and induces apoptosis, cell cycle arrest and COX activity in osteosarcoma cells. |
| M7737 | Concanamycin A (Folimycin) | Concanamycin A (Folimycin) is a macrolide antibiotic and a specific vacuolar type H+-ATPase (V-ATPase) inhibitor. |
| M7521 | Methyl paraben | Methyl paraben (Methyl 4-hydroxybenzoate) is an anti-fungal agent often used in a variety of cosmetics, personal-care products and food preservatives. |
| M7490 | Withaferin A | Withaferin A is a steroidal ester isolated from nightfruit, which can inhibit the activity of NF-kB, target vimentin, and has anti-inflammatory, anti-tumor and other effects. |
| M7409 | Thapsigargin | Thapsigargin is an endoplasmic reticulum (ER) stress inducer, it is also an inhibitor of microsomal Ca2+-ATPase. |
| M7029 | Nigericin sodium salt | Nigericin (NSC 292567) sodium salt is a selective K+ ionophore, Nigericin sodium salt is also an NLRP3 activator which can activate NLRP3 inflammasome to induce pro-inflammatory and immunostimulatory processes. |
| M6991 | Monensin sodium | Monensin Sodium is an antibiotic secreted by Streptomyces Cinnamonensis. Monensin Sodium is an ionic carrier that mediates Na+/H+ exchange. Monensin sodium causes the enlargement of cellular multivesicular bodies (MVBs) and regulates secretion of exosomes. |
| M6238 | Lanolin | Lanolin is a complex waxy substance composed of varying quantities of long-chain waxy esters and lanolin alcohols, acids and polycarbons, used as adjuvant. |
| M6209 | Rotenone | Rotenone is an inhibitor of mitochondrial electron transport at NADH:ubiquinone oxidoreductase, and is used to induce a Parkinson-like syndrome as an experimental model in rats. |
| M5961 | Silibinin | Silibinin, the main flavonoid extracted from the milk thistle Silybum marianum, displays hepatoprotective properties in acute and chronic liver injury. |
| M5868 | Penicillin G Sodium | Penicillin G Sodium is a β-lactam antibiotic produced by Penicillin spp. |
| M5791 | Mitomycin C | Mitomycin C (Ametycine) is an antineoplastic antibiotic by inhibiting DNA synthesis. Mitomycin C (Ametycine) is a DNA cross-linking agent and induces DNA damaging. Mitomycin C is an ADC Cytotoxin and induces apoptosis. |
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