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Diosgenin is a plant steroid which induces apoptosis in colon cancer cell lines and induces apoptosis, cell cycle arrest and COX activity in osteosarcoma cells. Diosgenin can inhibit STAT3 signaling pathway.
J Affect Disord. 2023 Jan 15;321:242-252.
Gut microbiota mediated inflammation, neuroendocrine and neurotrophic functions involved in the antidepressant-like effects of diosgenin in chronic restraint stress
Diosgenin purchased from AbMole
| Molecular Weight | 414.62 |
| Formula | C27H42O3 |
| CAS Number | 512-04-9 |
| Solubility (25°C) | chloroform 5 mg/mL ethanol 8 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Prajya Arya, et al. Diosgenin a steroidal compound: An emerging way to cancer management
[2] Shi-Qing Zhang, et al. Research on anti-tumor natural product diosgenin
[3] Zhongyi Sun, et al. Pathway design and key enzyme analysis of diosgenin biosynthesis
[5] Fang-Chun Wu, et al. Effects of diosgenin and its derivatives on atherosclerosis
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