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Cat. No. M8807
Perillaldehyde Structure

Perillal; PAE

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25mg USD 90  USD90 In stock
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Quality Control & Documentation
Biological Activity

Perillaldehyde inhibits BaP-induced AHR activation and ROS production, inhibits BaP/AHR-mediated release of the CCL2 chemokine, and activats the NRF2/HO1 antioxidant pathway.

Product Citations
Chemical Information
Molecular Weight 150.22
Formula C10H14O
CAS Number 18031-40-8
Storage 2-8°C, sealed
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.


[1] Yoko Fuyuno, et al. Oxid Med Cell Longev. Perillaldehyde Inhibits AHR Signaling and Activates NRF2 Antioxidant Pathway in Human Keratinocytes

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Keywords: Perillaldehyde, Perillal; PAE supplier, Aryl hydrocarbon Receptor, inhibitors, activators

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