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AhR Aryl Hydrocarbon Receptor


Cat.No.  Name Information
M10941 Tapinarof Tapinarof (WBI-1001) is a Frist in class aromatic hydrocarbon receptor (AhR) agonist with EC50 of 13 nM. Tapinarof reduced skin inflammation in mice. It can effectively inhibit inflammatory cytokines, regulate skin barrier protein expression and antioxidant activity.
M10486 GNF351 GNF351 is a full aryl hydrocarbon receptor (AHR) antagonist. GNF351 competes with a photoaffinity AHR ligand for binding to the AHR with an IC50 of 62 nM.
M10243 D-Kynurenine D-kynurenine is a metabolite of D-tryptophan, which can be used as a biological precursor of KYNA and 3-hydroxykynurenine.
M9723 L-Kynurenine L-Kynurenine is an aryl hydrocarbon receptor agonist.
M9714 CAY10465 CAY10465 is an analog of resveratrol acting as a potent and selective aryl hydrocarbon receptor agonist, with a Ki of 0.2 nM.
M9693 PDM2 PDM2 is a potent and selective aryl hydrocarbon receptor (AhR) antagonist, with a Ki of 1.2 nM.
M9490 YL-109 YL-109 is a novel anticancer agent, which can inhibit breast cancer cell growth and invasiveness in vitro and in vivo, YL-109 is also an STUB1 enhancer.
M8807 Perillaldehyde Perillaldehyde inhibits BaP-induced AHR activation and ROS production, inhibits BaP/AHR-mediated release of the CCL2 chemokine, and activats the NRF2/HO1 antioxidant pathway.
M7727 CH-223191 CH-223191 is a potent and specific aryl hydrocarbon receptor (AhR) antagonist. *The compound is unstable in solutions, freshly prepared is recommended
M4783 Diosimin Diosimin is a flavonoid glycoside found in citrus fruits, hyssop, and rosemary.
M2577 StemRegenin 1 StemRegenin 1 is an AhR inhibitor with IC50 of 127 nM.

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