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Diosimin

Cat. No. M4783
Diosimin Structure
Synonym:

Barosmin

Size Price Availability Quantity
20mg USD 45  USD50 In stock
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Quality Control
Biological Activity

Diosimin is a flavonoid glycoside found in citrus fruits, hyssop, and rosemary.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

Chemical Information
Molecular Weight 608.54
Formula C28H32O15
CAS Number 520-27-4
Purity >98%
Solubility DMSO ≥ 60 mg/mL
Storage at -20°C
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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: Diosimin, Barosmin supplier, AhR, inhibitors

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