About 1 result found for searched term "Diosimin" (0.061 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M4783 | Diosimin | Aryl hydrocarbon Receptor |
| Diosmin; Barosmin | ||
| Diosimin is a flavonoid glycoside found in citrus fruits, hyssop, and rosemary. Diosimin is also an agonist of the aryl hydrocarbon receptor (AhR), capable of upregulating the expression of p53, caspase 3, and caspase 9 in A431 cells, while downregulating the levels of Bcl-2 and matrix metalloproteinases (MMP-2 and MMP-9). Its metabolite, diosmetin, inhibits 3H-dopamine uptake in a dose-dependent manner with an IC50 value of 4 μM. | ||
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