Free shipping on all orders over $ 500

Coelenterazine

Cat. No. M9267

All AbMole products are for research use only, cannot be used for human consumption.

Coelenterazine Structure
Synonym:

CTZ; CLZN

Size Price Availability Quantity
1mg USD 120  USD120 In stock
5mg USD 360  USD360 In stock
10mg USD 600  USD600 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Coelenterazine (CTZ) can be catalyzed by luciferases, such as the sea pansy Renilla reniformis (Rluc) and the marine copepod Gaussia princeps (Gluc), which results in emission of blue light. In Gli36-Gluc- or Gli36-Rluc-expressing Gli36 cells, coelenterazine (8 μM/ml) shows a bioluminescence signal.

In vivo, in 4T1-implanted mouse, Coelenterazine detects cancer-associated superoxide anion and used to evaluate the role of superoxide anion in cancer cell biology and its role in pathology.

*The compound is unstable in solutions, freshly prepared is recommended



Product Citations
Chemical Information
Molecular Weight 423.46
Formula C26H21N3O3
CAS Number 55779-48-1
Solubility (25°C) Ethanol 2 mg/mL (Need ultrasonic
DMSO can inactivate Coelenterazine's activity)
Storage -20°C, protect from light, sealed
References

[1] Laura Bronsart, et al. Mol Imaging Biol . Reactive Oxygen Species Imaging in a Mouse Model of Inflammatory Bowel Disease

[2] Bronsart LL, et al. Mol Imaging Biol. Multimodality Imaging of Cancer Superoxide Anion Using the Small Molecule Coelenterazine.

[3] Morse D, et al. Mol Ther. A water-soluble coelenterazine for sensitive in vivo imaging of coelenterate luciferases.

[4] Pichler A, et al. Proc Natl Acad Sci U S A. Imaging reversal of multidrug resistance in living mice with bioluminescence: MDR1 P-glycoprotein transports coelenterazine.

[5] S Bhaumik, et al. Proc Natl Acad Sci U S A . Optical imaging of Renilla luciferase reporter gene expression in living mice

Related Fluorescent Dye Products
4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate

4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate is a fluorescent dye. 4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate can be used in the diagnosis of mucopolysaccharidosis IV A by detecting activity of galactose-6-sulphate sulphatase.

EverFluor Fl C5-Ceramide

BODIPY Fl C5-Ceramide is a Golgi-specific green fluorescent dye, which can visualise individual cells. The Golgi fluorescent probe is a BODIPY-labeled ceramide derivative, the synthesis of which occurs in the endoplasmic reticulum and can then be transported to the Golgi via ceramide transport protein (CERT) or vesicular translocation, allowing specific labeling of the dye. Ex/Em= 505 nm/512 nm

BODIPY TR Ceramide

BODIPY TR Ceramide (Golgi-Red Tracke) is a Golgi-specific fluorescent dye, which can visualise individual cells. The Golgi fluorescent probe is a BODIPY-labeled ceramide derivative, the synthesis of which occurs in the endoplasmic reticulum and can then be transported to the Golgi via ceramide transport protein (CERT) or vesicular translocation, allowing specific labeling of the dye. Ex/Em=589 nm/616 nm

Sulfo-Cy5.5 maleimide

Sulfo-Cy5.5 maleimide

Cyanine5.5 maleimide

Cyanine5.5 maleimide

  Catalog
Abmole Inhibitor Catalog




Keywords: Coelenterazine, CTZ; CLZN supplier, Fluorescent Dye, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.