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Kainic acid monohydrate

Cat. No. M7869

All AbMole products are for research use only, cannot be used for human consumption.

Kainic acid monohydrate Structure
Synonym:

KA

Size Price Availability Quantity
1mg USD 90  USD90 In stock
5mg USD 280  USD280 In stock
10mg USD 480  USD480 In stock
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Quality Control & Documentation
Biological Activity

Kainic acid monohydrate is an agonist at the kainate class of ionotropic glutamate receptors, which induces seizures and neurodegeneration in vivo and is used to induce experimental epilepsy in rodents and study the mechanisms of excitation-induced neuronal apoptosis.

Product Citations
Chemical Information
Molecular Weight 231.25
Formula C10H15NO4.H2O
CAS Number 58002-62-3
Solubility (25°C) Water 10 mg/mL (ultrasonic and warming)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Fabiola Pizzo, et al. Direct effects of the algal toxin, domoic acid, on ovarian function: Bovine granulosa and theca cells as an in vitro model

[2] A D Kovcs, et al. Kainate receptor-mediated activation of the AP-1 transcription factor complex in cultured rat cerebellar granule cells

[3] A Kohara, et al. In-vitro characterization of YM872, a selective, potent and highly water-soluble alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate receptor antagonist

[4] S Liljequist, et al. Effects of decahydroisoquinoline-3-carboxylic acid monohydrate, a novel AMPA receptor antagonist, on glutamate-induced CA2+ responses and neurotoxicity in rat cortical and cerebellar granule neurons

[5] A Ueki, et al. Effects of cholinergic drugs on learning impairment in ventral globus pallidus-lesioned rats

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Keywords: Kainic acid monohydrate, KA supplier, Animal Modeling, inhibitors, activators

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