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Concanamycin A (Folimycin) is a macrolide antibiotic and a specific vacuolar type H+-ATPase (V-ATPase) inhibitor. Concanamycin A inhibits acidification of organelles and perforin-mediated cytotoxicity. In the CD8(+) CTL clone, Concanamycin A (CMA) induced a marked DNA fragmentation and nuclear condensation characteristic of apoptosis.
Int J Mol Sci. 2021 Aug 16;22(16):8779.
Autophagy Mediates the Degradation of Plant ESCRT Component FREE1 in Response to Iron Deficiency
Concanamycin A (Folimycin) purchased from AbMole
Molecular Weight | 866.09 |
Formula | C46H75NO14 |
CAS Number | 80890-47-7 |
Solubility (25°C) | Limited soluble in DMSO |
Storage | 2-8°C, dry, sealed |
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Products are for research use only. Not for human use. We do not sell to patients.
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