About 30 results found for searched term "ATPase" (0.065 seconds)
Cat.No. | Name | Target |
---|---|---|
M2093 | Enoxacin | Anti-infection |
AT 2266; CI 919 | ||
Enoxacin is a small molecule inhibitor of binding between the B2-subunit of vacuolar H+-ATPase (V-ATPase) and microfilaments. | ||
M2294 | Brefeldin A | ATPase |
BFA; Cyanein; Decumbin | ||
Brefeldin A is a lactone antibiotic and ATPase inhibitor for protein transport with IC50 of 0.2 μM in HCT 116 cells. Brefeldin A is also an autophagy and mitophagy inhibitor. Brefeldin A is a CRISPR/Cas9 activator. Brefeldin A inhibits HSV-1 and has anti-cancer activity. | ||
M2459 | (-)-Blebbistatin | Myosin |
(S)-(-)-Blebbistatin | ||
(-)-Blebbistatin is a cell-permeable inhibitor for non muscle myosin II ATPase with IC50 of ~2 μM, does not inhibit myosin light chain kinase, inhibits contraction of the cleavage furrow without disrupting mitosis or contractile ring assembly. *The compound is unstable in solutions, freshly prepared is recommended | ||
M2474 | BTB06584 | ATPase |
BTB06584 is an IF1-dependent, selective inhibitor of the mitochondrial F1 Fo-ATPase. | ||
M2904 | Ouabain | ATPase |
Ouabain is a selective Na+/K+, -ATPase inhibitor, binds to α2 /α3 subunit with Ki of 41 nM/15 nM. | ||
M3449 | PF-3716556 | Potassium Channel |
PF 3716556 is a potent and selective P-CAB (potassium-competitive acid blocker), with pIC50 of 6.026 and 7.095 for the inhibition of porcine H+,K+-ATPase activity in ion-leaky and ion-tight assay, respectively, inhibits gastric acid secretion, displays no activity at Na+ | ||
M3696 | Rostafuroxin | ATPase |
PST 2238 | ||
Rostafuroxin, a novel antihypertensive compound, acts as a selective inhibitor of srC-SH2 interaction with Na, K-ATPase activated by mutated adducin and Wabin in vivo. | ||
M3707 | Rabeprazole Sodium | Proton Pump |
LY307640 sodium | ||
Rabeprazole is a frequently used second-generation proton pump inhibitor (PPI) that irreversibly inactivates gastric H+/K+-ATPase. | ||
M3935 | Digoxin | Sodium Channel |
12β-Hydroxydigitoxin | ||
Digoxin is a potent inhibitor of Na+/K+-ATPase, has the potential for arrhythmia and heart failure. | ||
M3987 | Ginsenoside Rb1 | Sodium Channel |
Gynosaponin C; Gypenoside III | ||
Ginsenoside Rb1 is an ingredient in the Chinese medicine Panax ginseng. Ginsenoside inhibition Na, K-ATPase++ activityIC50 6.3±1.0 μM. Ginsenoside Rb1 also inhibits IRAK-1 activation and phosphorylation of NF-κB p65. | ||
M4339 | Bufalin | Sodium Channel |
Bufalin is a potent Na+/K+-ATPase inhibitor, binds to the subunit α1, α2 and α3, with Kd of 42.5, 45 and 40 nM respectively, it has anti-cancer activity. | ||
M4765 | Oleandrin | Sodium Channel |
Oleandrin (PBI-05204) inhibited Na+, K+ -atPase activity with IC50 of 620 nM. | ||
M4953 | Bafilomycin A1 | Proton Pump |
Baf-A1;BafA1 | ||
Bafilomycin A1 (BafA1) is a vacuolar H+-ATPase inhibitor with IC50 of 0.44 nM. | ||
M5161 | Sodium orthovanadate | ATPase |
Sodium vanadate | ||
Sodium orthovanadate is an alkaline phosphatase and (Na,K)-ATPase inhibitor with IC50 of 10 μM. | ||
M5285 | Ilaprazole | Proton Pump |
IY-81149 | ||
Ilaprazole, a substituted benzimidazole, is a new candidate drug that is an H+ /K+ ATPase inhibitor designed for the treatment of gastric ulcers. | ||
M5409 | Amiodarone hydrochloride | Potassium Channel |
Amiodarone HCl is a sodium/potassium-ATPase inhibitor and an autophagy activator, used to treat various types of cardiac dysrhythmias. | ||
M5633 | Pantoprazole sodium | Proton Pump |
SKF96022 sodium, BY-1023 sodium | ||
Pantoprazole is a proton pump inhibitor drug that inhibits gastric acid secretion. It works on gastric parietal cells to irreversibly inhibit (H+/K+)-ATPase function and suppress the production of gastric acid. | ||
M9118 | Chebulinic acid | DNA/RNA Synthesis |
NSC69862 | ||
Chebulinic acid is a potent natural inhibitor of M. tuberculosis DNA gyrase, also can inhibit SMAD-3 phosphorylation, inhibit H+ K+-ATPase activity. | ||
M6194 | Esomeprazole Magnesium trihydrate | Autophagy |
(S)-Omeprazole magnesium trihydrate | ||
Esomeprazole Magnesium trihydrate is a proton pump inhibitor which reduces acid secretion through inhibition of the H+ / K+ ATPase in gastric parietal cells. | ||
M6501 | BHQ | Others |
2,5-Di-tert-butylhydroquinone | ||
BHQ is a inhibitor of SERCA ATPase. | ||
M6973 | ML 240 | Others |
ML 240 is a aTP-competitive inhibitor of p97 ATPase. | ||
M7103 | Paxilline | Potassium Channel |
Paxilline is a sERCA ATPase blocker. Also potent BK Ca channel blocker. | ||
M7280 | SCH 28080 | Others |
SCH 28080 is a h +,K +-ATPase inhibitor. | ||
M7409 | Thapsigargin | Calcium Channel |
Thapsigargin is a potent inhibitor of SERCA ATPase. | ||
M7575 | Apoptozole | HSP |
Apoptozole is an inhibitor of the ATPase domain of Hsc70 and Hsp70, with Kds of 0.21 and 0.14 μM, respectively, and can induce apoptosis. | ||
M7624 | 2,3-Butanedione monoxime | Myosin |
Biacetyl monoxime; Diacetyl monoxime; DAM | ||
2,3-Butanedione Monoxime (BDM) is a myosin ATPASE inhibitor. 2,3-Butanedione Monoxime is a skeletal and cardiac muscle contraction inhibitor. 2,3-Butanedione monoxime induces sarcoplasmic reticulum Ca2+ release. | ||
M7732 | CGP-37157 | Others |
Specific inhibitor of mitochondrial Na+/Ca2+ exchange as well as sarcoplasmic reticulum calcium-stimulated ATPase and possibly other calcium channels. | ||
M7737 | Concanamycin A (Folimycin) | ATPase |
Folimycin; CMA | ||
Concanamycin A (Folimycin) is a macrolide antibiotic and a specific vacuolar type H+-ATPase (V-ATPase) inhibitor. | ||
M7980 | Ouabain octahydrate | Others |
Acocantherine; G-Strophanthin | ||
Cardiac glycoside, inhibits Na(+)/K(+) ATPase, regulates transcription of MDR (increase, Pgp) and MRP (increase MRP1 and decrease CFTR, cyctic fibrosis transport receptor or cAMP-activated Cl- channel) genes, also alters localization of MRP1. | ||
M8185 | Strophanthidin | Others |
Strophanthidin is a cardiotonic steroid that elevates the activity of Na+/K+-ATPase in cardiac myocytes. |
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