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 About 30 results found for searched term "ATPase" (0.07 seconds)

Cat.No.  Name Target
M2093 Enoxacin Anti-infection
AT 2266; CI 919
Enoxacin is a small molecule inhibitor of binding between the B2-subunit of vacuolar H+-ATPase (V-ATPase) and microfilaments.
M2294 Brefeldin A ATPase
BFA; Cyanein; Decumbin
Brefeldin A is a lactone antibiotic and ATPase inhibitor for protein transport with IC50 of 0.2 μM in HCT 116 cells. Brefeldin A is also an autophagy and mitophagy inhibitor. Brefeldin A is a CRISPR/Cas9 activator. Brefeldin A inhibits HSV-1 and has anti-cancer activity.
M2459 (-)-Blebbistatin Myosin
(S)-(-)-Blebbistatin
(-)-Blebbistatin is a cell-permeable inhibitor for non muscle myosin II ATPase with IC50 of ~2 μM, does not inhibit myosin light chain kinase, inhibits contraction of the cleavage furrow without disrupting mitosis or contractile ring assembly. *The compound is unstable in solutions, freshly prepared is recommended
M2474 BTB06584 ATPase
BTB06584 is an IF1-dependent, selective inhibitor of the mitochondrial F1 Fo-ATPase.
M2904 Ouabain ATPase
Ouabain is a selective Na+/K+, -ATPase inhibitor, binds to α2 /α3 subunit with Ki of 41 nM/15 nM.
M3449 PF-3716556 Potassium Channel
PF 3716556 is a potent and selective P-CAB (potassium-competitive acid blocker), with pIC50 of 6.026 and 7.095 for the inhibition of porcine H+,K+-ATPase activity in ion-leaky and ion-tight assay, respectively, inhibits gastric acid secretion, displays no activity at Na+
M3696 Rostafuroxin ATPase
PST 2238
Rostafuroxin, a novel antihypertensive compound, acts as a selective inhibitor of srC-SH2 interaction with Na, K-ATPase activated by mutated adducin and Wabin in vivo.
M3707 Rabeprazole Sodium Proton Pump
LY307640 sodium
Rabeprazole is a frequently used second-generation proton pump inhibitor (PPI) that irreversibly inactivates gastric H+/K+-ATPase.
M3935 Digoxin Sodium Channel
12β-Hydroxydigitoxin
Digoxin is a potent inhibitor of Na+/K+-ATPase, has the potential for arrhythmia and heart failure.
M3987 Ginsenoside Rb1 Sodium Channel
Gynosaponin C; Gypenoside III
Ginsenoside Rb1 is an ingredient in the Chinese medicine Panax ginseng. Ginsenoside inhibition Na, K-ATPase++ activityIC50 6.3±1.0 μM. Ginsenoside Rb1 also inhibits IRAK-1 activation and phosphorylation of NF-κB p65.
M4339 Bufalin Sodium Channel
Bufalin is a potent Na+/K+-ATPase inhibitor, binds to the subunit α1, α2 and α3, with Kd of 42.5, 45 and 40 nM respectively, it has anti-cancer activity.
M4765 Oleandrin Sodium Channel
Oleandrin (PBI-05204) inhibited Na+, K+ -atPase activity with IC50 of 620 nM.
M4953 Bafilomycin A1 Proton Pump
Baf-A1;BafA1
Bafilomycin A1 (BafA1) is a vacuolar H+-ATPase inhibitor with IC50 of 0.44 nM.
M5161 Sodium orthovanadate ATPase
Sodium vanadate
Sodium orthovanadate is an alkaline phosphatase and (Na,K)-ATPase inhibitor with IC50 of 10 μM.
M5285 Ilaprazole Proton Pump
IY-81149
Ilaprazole, a substituted benzimidazole, is a new candidate drug that is an H+ /K+ ATPase inhibitor designed for the treatment of gastric ulcers.
M5409 Amiodarone hydrochloride Potassium Channel
Amiodarone HCl is a sodium/potassium-ATPase inhibitor and an autophagy activator, used to treat various types of cardiac dysrhythmias.
M5633 Pantoprazole sodium Proton Pump
SKF96022 sodium, BY-1023 sodium
Pantoprazole is a proton pump inhibitor drug that inhibits gastric acid secretion. It works on gastric parietal cells to irreversibly inhibit (H+/K+)-ATPase function and suppress the production of gastric acid.
M9118 Chebulinic acid DNA/RNA Synthesis
NSC69862
Chebulinic acid is a potent natural inhibitor of M. tuberculosis DNA gyrase, also can inhibit SMAD-3 phosphorylation, inhibit H+ K+-ATPase activity.
M6194 Esomeprazole Magnesium trihydrate Autophagy
(S)-Omeprazole magnesium trihydrate
Esomeprazole Magnesium trihydrate is a proton pump inhibitor which reduces acid secretion through inhibition of the H+ / K+ ATPase in gastric parietal cells.
M6501 BHQ Others
2,5-Di-tert-butylhydroquinone
BHQ is a inhibitor of SERCA ATPase.
M6973 ML 240 Others
ML 240 is a aTP-competitive inhibitor of p97 ATPase.
M7103 Paxilline Potassium Channel
Paxilline is a sERCA ATPase blocker. Also potent BK Ca channel blocker.
M7280 SCH 28080 Others
SCH 28080 is a h +,K +-ATPase inhibitor.
M7353 Tamoxifen Estrogen Receptor
ICI47699; Z-Tamoxifen; trans-Tamoxifen
Tamoxifen is an orally active, selective estrogen receptor partial agonist/antagonist. Tamoxifen is a potent Hsp90 activator and enhances the Hsp90 molecular chaperone ATPase activity. Tamoxifen also potent inhibits infectious EBOV Zaire and Marburg (MARV) with IC50 of 0.1 µM and 1.8 µM, respectively.
M7409 Thapsigargin Calcium Channel
Thapsigargin is an endoplasmic reticulum (ER) stress inducer, it is also an inhibitor of microsomal Ca2+-ATPase.
M7575 Apoptozole HSP
Apoptozole is an inhibitor of the ATPase domain of Hsc70 and Hsp70, with Kds of 0.21 and 0.14 μM, respectively, and can induce apoptosis.
M7624 2,3-Butanedione monoxime Myosin
Biacetyl monoxime; Diacetyl monoxime; DAM
2,3-Butanedione Monoxime (BDM) is a myosin ATPASE inhibitor. 2,3-Butanedione Monoxime is a skeletal and cardiac muscle contraction inhibitor. 2,3-Butanedione monoxime induces sarcoplasmic reticulum Ca2+ release.
M7732 CGP-37157 Others
Specific inhibitor of mitochondrial Na+/Ca2+ exchange as well as sarcoplasmic reticulum calcium-stimulated ATPase and possibly other calcium channels.
M7737 Concanamycin A (Folimycin) ATPase
Folimycin; CMA
Concanamycin A (Folimycin) is a macrolide antibiotic and a specific vacuolar type H+-ATPase (V-ATPase) inhibitor.
M7980 Ouabain octahydrate Others
Acocantherine; G-Strophanthin
Cardiac glycoside, inhibits Na(+)/K(+) ATPase, regulates transcription of MDR (increase, Pgp) and MRP (increase MRP1 and decrease CFTR, cyctic fibrosis transport receptor or cAMP-activated Cl- channel) genes, also alters localization of MRP1.



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