All AbMole products are for research use only, cannot be used for human consumption.
Tamoxifen is an orally active, selective estrogen receptor partial agonist/antagonist. Tamoxifen is a potent Hsp90 activator and enhances the Hsp90 molecular chaperone ATPase activity. Tamoxifen also potent inhibits infectious EBOV Zaire and Marburg (MARV) with IC50 of 0.1 µM and 1.8 µM, respectively. Tamoxifen exhibits antiestrogenic effects in mammary tissue and estrogen-like effects in bone. Tamoxifen activates autophagy and induces apoptosis. Tamoxifen also can induce gene knockout of CreER(T2) transgenic mouse.
Science Immunology. 2024 Aug 02.
cGAS-activated endothelial cell–T cell cross-talk initiates tertiary lymphoid structure formation
Tamoxifen purchased from AbMole
EMBO Mol Med. 2023 Dec.
MYSM1 acts as a novel co-activator of ERα to confer antiestrogen resistance in breast cancer
Tamoxifen purchased from AbMole
Biomater Adv. 2023 Mar;146:213301.
Breast cancer cells interact with tumor-derived extracellular matrix in a molecular subtype-specific manner
Tamoxifen purchased from AbMole
Nature. 2020 Dec;588(7839):664-669.
Creation of bladder assembloids mimicking tissue regeneration and cancer
Tamoxifen purchased from AbMole
| Molecular Weight | 371.51 |
| Formula | C26H29NO |
| CAS Number | 10540-29-1 |
| Solubility (25°C) | DMSO 30 mg/mL Ethanol 40 mg/mL |
| Storage | -20°C, protect from light |
[1] Susanne Feil, et al. Methods Mol Biol. Inducible Cre mice
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Products are for research use only. Not for human use. We do not sell to patients.
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