About 7 results found for searched term "Tamoxifen" (0.075 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M2280 | Tamoxifen Citrate (ICI 46474) | Estrogen Receptor |
| ICI 46474; Istubal; Nolvadex | ||
| Tamoxifen Citrate is an antagonist of the estrogen receptor by competitive inhibition of estrogen binding. | ||
| M7353 | Tamoxifen | Estrogen Receptor |
| ICI47699; Z-Tamoxifen; trans-Tamoxifen | ||
| Tamoxifen is an orally active, selective estrogen receptor partial agonist/antagonist. Tamoxifen is a potent Hsp90 activator and enhances the Hsp90 molecular chaperone ATPase activity. Tamoxifen also potent inhibits infectious EBOV Zaire and Marburg (MARV) with IC50 of 0.1 µM and 1.8 µM, respectively. | ||
| M7776 | N-Desmethyltamoxifen HCl | Others |
| N-Desmethyltamoxifen HCl is the primary metabolite of tamoxifen. | ||
| M7839 | (E/Z)-4-Hydroxytamoxifen | Estrogen Receptor |
| Afimoxifene; 4-OHT | ||
| (E/Z)-4-Hydroxytamoxifen is the racemate of (Z)-4-Hydroxytamoxifen and (E)-4-Hydroxytamoxifen and a modulator of the estrogen receptor (ER). | ||
| M10252 | 4-Hydroxytamoxifen | Estrogen Receptor |
| (Z)-4-Hydroxytamoxifen; trans-4-Hydroxytamoxifen; (Z)-Afimoxifene | ||
| 4-Hydroxytamoxifen ((Z)-4-Hydroxytamoxifen) is an orally active, selective estrogen receptor modulator (SERM). | ||
| M14627 | Droloxifene | Estrogen Receptor |
| 3-Hydroxytamoxifen | ||
| Droloxifene, a Tamoxifen derivative, is an orally active and selective estrogen receptor modulator. | ||
| M29903 | N-Desmethyltamoxifen | PKC |
| N-Desmethyltamoxifen is the major metabolite of tamoxifen in humans. N-Desmethyltamoxifen, a poor antiestrogen, is a ten-fold more potent protein kinase C (PKC) inhibitor than Tamoxifen. N-Desmethyltamoxifen is also a potent regulator of ceramide metabolism in human AML cells, limiting ceramide glycosylation, hydrolysis, and sphingosine phosphorylation. | ||
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