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N-Desmethyltamoxifen is the major metabolite of tamoxifen in humans. N-Desmethyltamoxifen, a poor antiestrogen, is a ten-fold more potent protein kinase C (PKC) inhibitor than Tamoxifen. N-Desmethyltamoxifen is also a potent regulator of ceramide metabolism in human AML cells, limiting ceramide glycosylation, hydrolysis, and sphingosine phosphorylation.
| Molecular Weight | 357.49 |
| Formula | C25H27NO |
| CAS Number | 31750-48-8 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Related PKC Products |
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Products are for research use only. Not for human use. We do not sell to patients.
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