About 30 results found for searched term "THI" (0.004 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1856 | Thiazovivin | ROCK |
| Thiazovivin is a selective small molecule Rho-associated kinase (ROCK) inhibitor which significantly improves (200-fold) the efficiency of iPSC generation from human fibroblasts. | ||
| M2357 | 2-Thiouracil | NO Synthase |
| Thiouracil | ||
| 2-Thiouracil is a thiolated uracil derivative that is a known antihyperthyroid agent. | ||
| M2373 | Allylthiourea | Others |
| Thiosinamine; N-Allylthiourea | ||
| Allylthiourea is a metabolic inhibitor that selective inhibits ammonia oxidation. | ||
| M2387 | Aminothiazole | Antibiotic |
| 2-Aminothiazole; 2-Thiazolylamine | ||
| Aminothiazole can be used as a thyroid inhibitor and it has antibacterial activity. | ||
| M2444 | Benzthiazide | Carbonic Anhydrase |
| Benzothiazide | ||
| Benzthiazide is a thiazide diuretic, promoting water loss from the body. | ||
| M2496 | Catharanthine | Calcium Channel |
| (+)-3,4-Didehydrocoronaridine | ||
| Catharanthine inhibits nicotinic receptor mediated diaphragm contractions with IC50 of 59.6 μM | ||
| M2501 | Cepharanthine | NF-κB |
| NSC-623442 | ||
| Cepharanthine is a biscoclaurine alkaloid inhibiting tumor necrosis factor (TNF)-α-mediated NFκB stimulation, plasma membrane lipid peroxidation and platelet aggregation and suppressing cytokine production. | ||
| M2548 | Cysteamine hydrochloride | Animal Modeling |
| β-MEA Hydrochloride; β-Mercaptoethylamine Hydrochloride; 2-Aminoethanethiol Hydrochloride | ||
| Cysteamine HCl, the hydrochloride form of Cysteamine, is also a transglutaminase 2 (TGM2) inhibitor, which can be used to induce gastrointestinal disorders in a mouse model as well as a duodenal ulcer model. In addition, Cysteamine HCl has the ability to modulate the activity of dopamine neurons in the striatum of awake, freely moving rats by inhibiting the increased dopamine release from amphetamine, and has antioxidant activity. | ||
| M2565 | PR-619 | Deubiquitinase |
| 2,6-Diamino-3,5-dithiocyanopyridine | ||
| PR-619 is a broad-spectrum reversible DUB (deubiquitinating enzyme) inhibitor of USP2, USP4, USP5, USP7 and USP8 with an EC50 of 3-9 μM. PR-619 also induces endoplasmic reticulum stress and endoplasmic reticulum stress-associated apoptosis. | ||
| M2579 | Catharanthine sulfate | Others |
| Catharanthine inhibits nicotinic receptor mediated diaphragm contractions with IC50 of 59.6 μM. | ||
| M2631 | Dibenzothiophene | Others |
| DBT; Diphenylene sulfide | ||
| Dibenzothiophene (DBT) is a model compound for organic sulfur in fossil fuels. | ||
| M2739 | Guanethidine Sulfate | Monoamine Oxidase |
| Guanethidine is an antihypertensive compound that reduces the release of catecholamines such as norepinephrine. | ||
| M2843 | Methyclothiazide | Carbonic Anhydrase |
| Methyclothiazide (MCTZ) is an orally active, substituted benzothiazide that also antagonizes extracellular voltage-dependent calcium channel (VDCC) activity. It can be used in the study of hypertension-related diseases. | ||
| M2844 | Methylthiouracil | NF-κB |
| MTU | ||
| Methylthiouracil is an anti-thyroid agent. Methylthiouracil inhibits TNF-α and IL-6 production and NF-κB and ERK1/2 activation. | ||
| M2887 | Norethindrone | Progesterone Receptor |
| Norethisterone | ||
| Norethindrone is a synthetic progestin, which mimic the actions of the endogenous ovarian hormone progesterone. | ||
| M2913 | Palbociclib Isethionate | CDK |
| PD 0332991 isethionate | ||
| Palbociclib (PD0332991) Isethionate is a highly selective inhibitor of CDK4/6 with IC50 of 11 nM/16 nM. It shows no activity against CDK1/2/5, EGFR, FGFR, PDGFR, InsR, etc. Phase 2/3. | ||
| M2936 | Phenothiazine | Dopamine Receptor |
| Thiodiphenylamine | ||
| Phenothiazine is a dopamine-2 (D2) receptor antagonist therefore decreases the effect of dopamine in the brain. | ||
| M3064 | Thiamet G | OGA/OGT |
| Thiamet G is a potent, selective O-GlcNAcase inhibitor with Kiof 21 nM, while exhibiting 37,000-fold selectivity over human lysosomal –hexosaminidase. | ||
| M3065 | Thioridazine hydrochloride | Dopamine Receptor |
| Thioridazine is a trifluoro-methyl phenothiazine derivative, which blocks postsynaptic mesolimbic dopaminergic D1 and D2 receptors in the brain. | ||
| M3066 | Thiostrepton | Antibiotic |
| Alaninamide, Bryamycin, Thiactin | ||
| Thiostrepton is a thiazole antibiotic which selectively inhibits FOXM1. Thiostrepton is a natural cyclic oligopeptide antibiotic, derived from several strains of strepromycetes. | ||
| M3137 | Zinc Pyrithione | Cuproptosis |
| ZnPyr | ||
| Zinc Pyrithione is an anti-fungal and anti-bacterial drug that disrupts membrane transport by blocking proton pumps and is a potent copper ion carrier that can be used in copper death (cuproptosis) studies. | ||
| M3170 | Lithium citrate | Others |
| Trilithium Citrate | ||
| Lithium citrate is a chemical compound of lithium and citrate that is used as a mood stabilizer in psychiatric treatment of manic states and bipolar disorder. | ||
| M3174 | Bendroflumethiazide | Others |
| Bendrofluazide | ||
| Bendroflumethiazide is a thiazide diuretic used to treat hypertension. | ||
| M3206 | Thiamphenicol | Antibiotic |
| Thiophenicol | ||
| Thiamphenicol is an antimicrobial antibiotic and a methyl-sulfonyl analogue of chloramphenicol. | ||
| M3258 | Thioguanine | DNA/RNA Synthesis |
| 6-Thioguanine; 6-TG; 2-Amino-6-mercaptopurine; 2-Amino-6-purinethiol | ||
| Thioguanine is a purine antimetabolite widely used in the treatment of acute lymphoblastic leukemia, autoimmune disorders (e.g., Crohn's disease, rheumatoid arthritis) and organ transplant recipients. | ||
| M3288 | Aminoglutethimide | Others |
| DL-Aminoglutethimide | ||
| Aminoglutethimide is an aromatase inhibitor with IC50 of 10 μM. | ||
| M3314 | Ethionamide | Antibiotic |
| 2-ethylthioisonicotinamide | ||
| Ethionamide(2-ethylthioisonicotinamide) is an antibiotic used in the treatment of tuberculosis. | ||
| M3315 | Thiabendazole | Mitochondrial Related |
| 2-(4-Thiazolyl)benzimidazole | ||
| Thiabendazole inhibites the mitochondrial helminth-specific enzyme, fumarate reductase, with anthelminthic property. | ||
| M3390 | Disulfiram | Pyroptosis |
| Tetraethylthiuram disulfide; TETD | ||
| Disulfiram (Tetraethylthiuram disulfide) is a specific inhibitor of aldehyde-dehydrogenase (ALDH1). Disulfiram is used in the study of chronic alcoholism, with acute sensitivity to alcohol, and is a potent copper ion-carrier that can be used in cuproptosis studies. | ||
| M3392 | Ethinyl Estradiol | Estrogen Receptor |
| 17α-Ethynylestradiol; Ethynylestradiol | ||
| Ethinyl Estradiol (Ethinylestradiol) is an orally bio-active estrogen used in almost all modern formulations of combined oral contraceptive pills. | ||
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.
