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The thiopurine compounds are purine antimetabolites widely used in the treatment of acute lymphoblastic leukemia, autoimmune disorders (e.g., Crohn’s disease, rheumatoid arthritis) and organ transplant recipients.
Clin Epigenetics. 2021 Jul 22;13(1):142.
Genome-wide DNA methylome analysis identifies methylation signatures associated with survival and drug resistance of ovarian cancers
Thioguanine purchased from AbMole
| Molecular Weight | 167.19 |
| Formula | C5H5N5S |
| CAS Number | 154-42-7 |
| Solubility (25°C) | DMSO 7 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Femke Crouwel, et al. Thioguanine Therapy in Inflammatory Bowel Diseases. A Practical Guide
[4] Kirstin M Taylor, et al. Is there a role for thioguanine therapy in IBD in 2017 and beyond?
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