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Zinc Pyrithione

Cat. No. M3137

All AbMole products are for research use only, cannot be used for human consumption.

Zinc Pyrithione Structure
Synonym:

ZnPyr

Size Price Availability Quantity
500mg USD 45  USD45 In stock
1g USD 60  USD60 In stock
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Quality Control & Documentation
Biological Activity

Zinc Pyrithione is an anti-fungal and anti-bacterial drug that disrupts membrane transport by blocking proton pumps and is a potent copper ion carrier that can be used in copper death (cuproptosis) studies.

Chemical Information
Molecular Weight 317.7
Formula C10H8N2O2S2Zn
CAS Number 13463-41-7
Solubility (25°C) DMSO 20 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Sean E Mangion, et al. Targeted Delivery of Zinc Pyrithione to Skin Epithelia

[2] Cheryl Leong, et al. Effect of zinc pyrithione shampoo treatment on skin commensal Malassezia

[3] James R Schwartz. Zinc Pyrithione: A Topical Antimicrobial With Complex Pharmaceutics

[4] Mrinal Gupta, et al. Zinc therapy in dermatology: a review

[5] Eugene Guthery, et al. Zinc pyrithione in alcohol-based products for skin antisepsis: persistence of antimicrobial effects

Related Cuproptosis Products
Cu(II)-Elesclomol

Cu(II)-Elesclomol is a Cu2+ complex of Elesclomol. Cu(II)-Elesclomol induces cuproptosis. Cu(II)-Elesclomol also inducesapoptosis, causes a G1 cell cycle block and induces DNA double strand breaks in K562 cells.

DL-Penicillamine

DL-Penicillamine is a copper chelating agent. DL-Penicillamine can cause pyridoxine deficiency and then induce optic axial neuritis. DL-Penicillamine can also depress primary immune response.

UM4118

UM4118 is a copper ionophore which can initiate a mitochondrial-based noncanonical form of cell death known as cuproptosis. UM4118 exhibits high sensitivity in SF3B1-mutated and adverse risk acute myeloid leukemia (AML), and can be used for AML research.

Ammonium tetrathiomolybdate

Ammonium tetrathiomolybdate is a copper chelator and also is a class of sulfide donor. Ammonium tetrathiomolybdate has neuroprotection effects. Tetrathiomolybdate, an orally active anti-copper agent, reduces copper levels in the body.

2,2'-Bipyridine

2,2'-Bipyridine has been used in the preparation of copper(II)-bipyridine-naringenin complexes. It can be used for the preparation of 2,2'-bipyridine hydrobromide. 2,2'-Bipyridine has good redox stability and glucose elevating activity.

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Keywords: Zinc Pyrithione, ZnPyr supplier, Cuproptosis, inhibitors, activators

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