Cuproptosis Cuproptosis

Inhibitors

Cat.No.	Name	Information
M5377	8-Hydroxyquinoline	8-hydroxyquinoline is a mono-proton bicyclic chelator that is used as a preservative, disinfectant, and insecticide and as a transcription inhibitor. Is a kind of antiseptic with mild inhibition of fungi, bacteria, insect repellent, killing amoeba characteristics, is a strong copper ion carrier, can be used for copper death research.
M3390	Disulfiram	Disulfiram is used in the study of chronic alcoholism with acute sensitivity to alcohol and is a potent copper ion-carrier that can be used in the study of copper death.
M3137	Zinc Pyrithione	Zinc Pyrithione is an anti-fungal and anti-bacterial drug that disrupts membrane transport by blocking proton pumps and is a potent copper ion carrier that can be used in copper death studies.
M2891	NSC 319726	NSC 319726 is a p53(R175) mutant activator that inhibits the growth of cells expressing mutant p53. It acts on p53(R175) mutant with IC50 of 8 nM and has no inhibition on p53 wild-type cells. It is a powerful copper ion-carrier and can be used for the study of copper death.
M2083	Elesclomol	Elesclomol (STA-4783) is a novel oxidative stress inducer that acts on tumor cells and promotes their apoptosis, and is a strong copper ion carrier that can be used for copper death research.