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Norethindrone is a synthetic progestin, which mimic the actions of the endogenous ovarian hormone progesterone.
Cell Experiment | |
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Cell lines | Human epithelial cervical cancer cells |
Preparation method | Thereafter, the cells were incubated with serum-free, phenol-free DMEM for 2 hrs, before treatment with 100 nM DEX, MPA, P4 and NET-A for 1 hr. Cells were crosslinked for 10 min at 37°C with1% formaldehyde and the reaction was stopped with 0.1 mM glycine for 5 min, shaking at room temperature. |
Concentrations | 100 nM |
Incubation time | 1 h |
Animal Experiment | |
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Animal models | Female Sprague-Dawley rats |
Formulation | corn oil |
Dosages | 3 μg/rat/day |
Administration | oral |
Molecular Weight | 298.42 |
Formula | C20H26O2 |
CAS Number | 68-22-4 |
Form | Solid |
Solubility (25°C) | DMSO 50 mg/mL |
Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
Related Progesterone Receptor Products |
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PR antagonist 1 is a selective progesterone receptor (PR) antagonist, and can be used for the research of a variety of progesterone-related diseases and disorders such as endometriosis and uterine fibroids. |
Trimegestone
Trimegestone (RU 27987) is an orally active 19-norpregnane progestin. |
Nomegestrol
Nomegestrol is a potent and orally available progestin, acts as a selective full progesterone receptor agonist, with a Kd of 5.44 nM for rat uterine progesterone receptor, and has moderate antiandrogenic activity and strong antiestrogenic activity. |
Allylestrenol
Allylestrenol is an anabolic steroid with progesterone activity and potential physiologic function as a progesterone receptor agonist that can be used in studies related to preterm labor. |
Cridanimod
Cridanimod is a potent progesterone receptor (PR) activator mediated through induction of IFNα and IFNβ expression. Cridanimod is a small-molecule immunomodulator and interferon inducer. |
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