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Thiamet G is a potent, selective O-GlcNAcase inhibitor with Kiof 21 nM, while exhibiting 37,000-fold selectivity over human lysosomal –hexosaminidase.
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Animal models | Healthy Sprague-Dawley rats |
Formulation | Drinking water (p.o.) |
Dosages | 200 mg/kg (p.o.), ~50 mg/kg (i.v.) |
Administration | Administrated by p.o. or i.v. |
Molecular Weight | 248.3 |
Formula | C9H16N2O4S |
CAS Number | 1009816-48-1 |
Solubility (25°C) | DMSO 30 mg/mL |
Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
Related OGA/OGT Products |
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GlcNAcstatin
GlcNAcstatin is a selective O-GlcNAcase (OGA) inhibitor with Ki of 4.6 pM. |
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