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Thiamphenicol (Thiophenicol) is an antimicrobial antibiotic and a methyl-sulfonyl analogue of chloramphenicol. Thiamphenicol (Thiophenicol) has a similar antibacterial spectrum to chloramphenicol. Thiamphenicol (Thiophenicol) inhibits protein synthesis in bacteria. Thiamphenicol (Thiophenicol) has a bacteriostatic action against a broad range of microorganisms, although it may be bactericidal for some species under some conditions, and in concentrations 3 to 5 times higher than the bacteriostatic concentrations. Thiamphenicol (Thiophenicol) is particularly used for the treatment of sexually transmitted infections and pelvic inflammatory disease.
Molecular Weight | 356.22 |
Formula | C12H15Cl2NO5S |
CAS Number | 15318-45-3 |
Form | Solid |
Solubility (25°C) | DMSO |
Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Kai Yang, et al. Removal of antibiotic thiamphenicol by bacterium Aeromonas hydrophila HS01
[3] Marta Tikhomirov, et al. Pharmacokinetics of florfenicol and thiamphenicol in ducks
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