About 30 results found for searched term "SEQ-9" (0.118 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M41042 | SEQ-9 | Antibiotic |
| SEQ-9 is an orally active Mycobacterium tuberculosis (Mtb) 23S bacterial ribosome inhibitor with an IC50 of approximately 170 nM for unmethylated Mtb ribosomes. | ||
| M53480 | HBV Seq2 aa:179-186 | Anti-infection |
| HBV Seq2 aa:179-186 serve as effective motifs for CTL response in H-2b system after in vitro restimulation of the primed T cells. | ||
| M53511 | HBV Seq2 aa:28-39 | Anti-infection |
| HBV Seq2 aa:28-39 is a HBsAg peptide, which binds to major histocompatibility complex (MHC) class I molecules. | ||
| M3892 | BMH-21 | DNA/RNA Synthesis |
| BMH-21 is a first-in-class DNA intercalator that binds to high-frequency GC-rich sequences in ribosomal DNA genes and can effectively and rapidly inhibit the transcription of RNA polymerase I (Pol I), leading to degradation of the Pol I catalytic subunit RPA194 and non-phosphorylation of histone H2AX. H2AX is not phosphorylated.BMH-21 has broad and potent antitumor activity in NCI60 cancer cell line and inhibits tumor growth in vivo. | ||
| M11235 | Recombinant Human PD-1 Protein(Fc) | Cytokines and Growth Factors |
| CD279; PDCD1 | ||
| Pd-1 (Programmed Cell death protein 1), also known as PDCD1, is an important immunosuppressive transmembrane protein expressed on the surface of T cells. The protein Sequence of this product is the expression of DNA Sequence encoding human PD-1 (NCBI Reference Sequence: NP_005009.2) with Fc label at the C-terminal. | ||
| M11382 | Recombined human IL-15 MAX (HEK293) | Cytokines and Growth Factors |
| Recombined human IL-15 MAX Protein sequence: DNA encoding human IL-10 (P40933) Bioactivity: Cell proliferation was measured with MO7e human megakaryocytic leukemia cells with an ED50 of 7-28 ng/mL | ||
| M11386 | Recombinant Human CD19 Protein (HEK293) | Cytokines and Growth Factors |
| Recombinant Human CD19 Protein (HEK293) Protein sequence: THE DNA sequence encoding human CD19 (UniProtKB/ Swiss-PROt: P15391.6) was expressed with His tag at the C-terminal. Bioactivity: Immobilized CD19 monoclonal antibody at 5μg/mL (100 μL/ well) can bind CD19 protein in a linear range of 5-100ng/mL | ||
| M11390 | Recombinant Human 4-1BB Protein (HEK293) | Cytokines and Growth Factors |
| TNFRSF9、4-1BB、CD137、CDw137、ILA | ||
| Recombinant Human 4-1BB Protein (HEK293) Protein sequence: DNA sequence encoding human 4-1BB (UniProtKB/ Swiss-PROt: Q07011.1) expressed with His tag at the C-terminal Bioactivity: 4-1BB, also known as CD137, is a member of the tumor necrosis factor receptor superfamily 9 (TNFRSF9) induced by lymphocyte activation (ILA), and is a costimulatory molecule of the tumor necrosis factor receptor superfamily. | ||
| M11471 | Recombinant Human CCL5 protein (E.coli) | Cytokines and Growth Factors |
| Protein construction: The DNA sequence encoding human CCL5 (SER24-SER91) was fused with the GST marker Biological activity: Chemokines for blood monocytes, memory T helper cells and eosinophils. Cause basophils to release histamine and activate eosinophils. | ||
| M15023 | Recombinant Human MCP-2/CCL8 (E. coli) | Cytokines and Growth Factors |
| Monocyte Chemoattractant Protein-2; HC14; SCYA8 | ||
| McP-2, a member of the chemokine family, is a group of 70-80 residues with significant sequence similarity. Protein structure: McP-2 (GLN24-PRO99), Accession # P80075. | ||
| M15041 | Recombinant Human MEC/CCL28 (E. coli) | Cytokines and Growth Factors |
| Chemokine (C-C motif) ligand 28; CCL-28; SCYA28 | ||
| CCL28 (CC chemokine ligand 28), a novel CC chemokine, was identified by TBLASTN search using the human Genome System (HGS) and Genbank dbEst databases using a consistent sequence of human chemokines. Protein structure: CCL28 (Ser20-Tyr127), Accession # ：Q9NRJ3. | ||
| M13751 | Arg-Gly-Asp-Ser | Integrin |
| RGDS peptide; Fibronectin tetrapeptide | ||
| Arg-Gly-Asp-Ser is an integrin binding sequence that inhibits integrin receptor function. Arg-Gly-Asp-Ser directly and specifically bind pro-caspase-8, pro-caspase-9 and pro-caspase-3, while it does not bind pro-caspase-1. | ||
| M15045 | Recombinant Mouse SDF-1α/CXCL12 (E. coli) | Cytokines and Growth Factors |
| SDF-1-α; SDF1α; CXCL-12; IRH | ||
| Stromal cell-derived factor-1 α / CXCL12 (SDF-1α) and SDF-1β, members of the α subfamily of chemokines lacking the ELR domain, were originally identified from mouse bone marrow stromal cell lines using a signal-sequence trap cloning strategy. Protein construction: SDF-1α/CXCL12 (Lys22-LYS89), Accession # : Q4FJL5. | ||
| M15087 | Recombinant Human Wnt3a (E. coli) | Cytokines and Growth Factors |
| MGC119418; MGC119419; MGC119420 | ||
| Recombinant human WnT-3A protein was produced by Escherichia coli expression system. The DNA sequence encoding human WNT3A (Ser19-Lys352) was fused to the His tag. Accession # P56704. | ||
| M15109 | Recombinant Mouse IL-10 (CHO) | Cytokines and Growth Factors |
| Mouse Interleukin-10 Protein | ||
| Recombinant Mouse IL-10 (CHO) belongs to the IL-10 family and shares more than 80% sequence homology with the Epstein-Barr Virus protein BCRFI. Measured in a cell proliferation assay using MC/9 cells, the ED50 is < 0.2 ng/ml. | ||
| M21344 | Recombinant Human CXCL16 (Val52-Lys190) (E.coli) | Cytokines and Growth Factors |
| C-X-C motif chemokine 16 | ||
| Protein Construct: DNA sequence encoding human CXCL16 (Val52-Lys190) fused to a His tag. Accession #: Q9H2A7. | ||
| M21345 | Recombinant Human CXCL16 (Pro49-Pro137) (E.coli) | Cytokines and Growth Factors |
| SR-PSOX，Small-inducible cytokine B16 | ||
| Protein Construct: DNA sequence encoding human CXCL16 (Pro49-Pro137) fused to a GST tag. Accession #: Q9H2A7. | ||
| M21346 | Recombinant Human Cuteaneous T-cell Attracting Chemokine/CCL27 (E.coli ) | Cytokines and Growth Factors |
| AA Sequence：FLLPPSTACC TQLYRKPLSD KLLRKVIQVE LQEADGDCHL QAFVLHLAQR SICIHPQNPS LSQWFEHQER KLHGTLPKLN FGMLRKMG.Accession: Q9Y4X3. | ||
| M21358 | Certepetide | Integrin |
| CEND-1; iRGD; LSTA1 | ||
| Certepetide (CEND-1) is a bifunctional cyclic peptide (a.k.a. iRGD). Certepetide is a tumor-penetrating peptide whose RGD motif interacts with alphav-integrins and activates neurofibrillary protein 1 (NRP-1) to transform the solid tumor microenvironment into a temporary drug pipeline. Sequence Shortening: Ac-CRGDKGPDC-NH2 (Disulfide bridge: Cys1-Cys9). | ||
| M21451 | Recombinant Human Cathepsin K protein (E.coli) | Cytokines and Growth Factors |
| CTSK；Cathepsin K；Cathepsin O；Cathepsin O2 | ||
| Protein construction: The DNA sequence encoding human CTSK (Ala115-Met329) is fused with His tag. Accession #P43235. | ||
| M25406 | Recombinant Human DLAT Protein (Baculovirus-Insect, His Tag) | Cytokines and Growth Factors |
| Dihydrolipoyl Transacetylase | ||
| The recombinant human DLAT consists of 581 amino acids and predicts a molecular mass of 62.1 kDa. A DNA sequence encoding the human DLAT (NP_001922.2) (Ser87-Leu647) was expressed with a polyhistidine tag at the N-terminus. | ||
| M27896 | Duocarmycin A | Antibiotic |
| Duocarmycin A, which is one of well-known antitumor antibiotics, is a DNA alkylator and efficiently alkylates adenine N3 at the 3′ end of AT-rich sequences in the DNA. Duocarmycin A, as a chemotherapeutic agent, results HLC-2 cells typically apoptotic changes, including chromatin condensation, sub-G1 accumulation in DNA histogram pattern, and decrease in procaspase-3 and 9 levels. | ||
| M29277 | Imsamotide | IDO |
| IDO194-214 | ||
| Imsamotide (IDO194-214) is a Indoleamine 2,3-Dioxygenase (IDO) peptide with sequences of DTLLKALLEIASCLEKALQVF, the IDO194-214. Imsamotide is also an immunological agent for active immunization, as well as an antineoplastic agent. | ||
| M31164 | Recombinant Human PPARA Protein (E.coli, His Tag) | Cytokines and Growth Factors |
| human PPAR-alpha; hPPARA | ||
| The recombinant Human PPARA consists of 276 amino acids and predicts a molecular mass of 31.36 kDa. A DNA sequence encoding the Human PPARA (Q07869) (Thr200-Tyr468) was expressed, with a polyhistidine tag at the N-terminus. | ||
| M31361 | Recombinant Human MRAP Protein (HEK293, hFc Tag) | Cytokines and Growth Factors |
| Melanocortin 2 Receptor Accessory Protein; FALP; B27 | ||
| MRAP is a single transmembrane domain accessory protein and a critical component of the hypothamo pituitary-adrenal axis. A DNA sequence encoding the human MRAP (Tyr59-Ser172) was expressed with the Fc region of human IgG1 at the N-terminus. | ||
| M45130 | NNC0385-0434 | PCSK9 |
| NNC0385-0434 is a peptide based on the epidermal growth-factor-like domain A of the human LDLR peptide. NNC0385-0434 competitively binds free PCSK9 and subsequently prevents PCSK9 binding to the LDLR. NNC0385-0434 is an orally active peptide small molecule PCSK9 inhibitor for atherosclerosis-related studies. | ||
| M50239 | Tertomotide hydrochloride | HSP |
| GV1001 | ||
| Tertomotide hydrochloride is a peptide consisting of 16 amino acids containing sequences derived from human telomerase reverse transcriptase (TERT).Tertomotide penetrates cells and interacts with HSP70 and HSP90, as well as inhibiting amyloid beta and tau, and inhibiting aging-related signaling in the brain. pathways, which could be used in aging and Alzheimer's disease related studies. | ||
| M50750 | Peptide C105Y | Others |
| Peptide C105Y, a synthetic and cell-penetrating peptide based on the amino acid sequence corresponding to residues 359-374 of α1-antitrypsin, enhances gene expression from DNA nanoparticles. | ||
| M54831 | Recombinant Human IL-36 gamma/IL-1 F9 Protein (E. coli) | Cytokines and Growth Factors |
| IL-1F9; interleukin 36 gamma | ||
| The recombinant human IL1F9 consisting of 169 amino acids and has a calculated molecular mass of 18.9 kDa. A DNA sequence encoding the human IL-1F9 isoform 1 (Met 1-Asp 169) was expressed. | ||
| M54832 | Recombinant Human IL-36 gamma/IL-1 F9 Protein (E. coli, aa 18-169, His Tag) | Cytokines and Growth Factors |
| interleukin 36 gamma; IL1F9 | ||
| The recombinant human IL1F9 consists of 168 amino acids and predicts a molecular mass of 19.1 KDa. A DNA sequence encoding the mature form of human IL1F9 (Ser18-Asp169) was expressed with a polyhistide tag at the N-terminus. | ||
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